Results 51 to 60 of about 235,302 (301)

The effect of inhaled heliox on peak flow rates in normal and brachycephalic dogs

Journal of Veterinary Internal Medicine, 2019
Background Heliox, a mixture of helium and oxygen, alleviates airway obstruction in people and improves air flow, and its use has been proposed in dogs.
Kathryn Benavides, Elizabeth Rozanski, John D. Anastasio, Daniela Bedenice   +3 more
doaj   +1 more source

Pulmonary function tests [PDF]

Canadian Anaesthetists’ Society Journal, 1956
Comroe and his associates in their very instructive and concise book on clinical physiology, entitled The Lung, said: “Tests of pulmonary function have proved of definite value both in diagnosis and in guiding therapy of patients with cardiopulmonary disorders.” I am sure that a larger utilization of these tests before operating on cardiopulmonary ...
openaire   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Recommendations for surveillance of pulmonary dysfunction among childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group

EClinicalMedicine
Summary: Childhood, adolescent, and young adult (CAYA) cancer survivors are at risk of pulmonary dysfunction. Current follow-up care guidelines are discordant.
Maria Otth, Rahel Kasteler, Renée L. Mulder, Jennifer Agrusa, Saro H. Armenian, Dana Barnea, Anne Bergeron, Neel S. Bhatt, Stephen J. Bourke, Louis S. Constine, Myrofora Goutaki, Daniel M. Green, Ulrike Hennewig, Veronique Houdouin, Melissa M. Hudson, Leontien Kremer, Philipp Latzin, Antony Ng, Kevin C. Oeffinger, Christina Schindera, Roderick Skinner, Grit Sommer, Saumini Srinivasan, Dennis C. Stokes, Birgitta Versluys, Nicolas Waespe, Daniel J. Weiner, Andrew C. Dietz, Claudia E. Kuehni   +28 more
doaj   +1 more source

Combined forced oscillation and fractional-order modeling in patients with work-related asthma: a case–control study analyzing respiratory biomechanics and diagnostic accuracy

BioMedical Engineering OnLine, 2020
Background Fractional-order (FrOr) models have a high potential to improve pulmonary science. These models could be useful for biomechanical studies and diagnostic purposes, offering accurate models with an improved ability to describe nature. This paper
Fábio Augusto d´Alegria Tuza, Paula Morisco de Sá, Hermano A. Castro, Agnaldo José Lopes, Pedro Lopes de Melo   +4 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Coaching patients during pulmonary function testing: A practical guide

Canadian Journal of Respiratory Therapy, 2015
Pulmonary function testing is a cornerstone in the diagnosis and management of individuals with respiratory disease. However, correct interpretation of pulmonary function data relies heavily on acceptable test quality, which in turn is dependent on ...
Heidi J Cheung, Lawrence Cheung
doaj  

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Lung involvement in systemic sclerosis [PDF]

Batna Journal of Medical Sciences
Introduction: Systemic sclerosis (SSc) is a connective tissue disease affecting the skin and internal organs, particularly the lungs, leading to significant morbidity and mortality.
Sihem KOURTAA, Sabrina HAID
doaj   +1 more source