Results 151 to 160 of about 58,255 (295)

Oxygen therapy in respiratory disorders

, 2012
PhDOxygen therapy remains a cornerstone of medical practice and is generally regarded as being safe. However, there is a lack of clinical evidence to support the routine use of oxygen therapy, and in certain conditions, injudicious oxygen may cause harm.
Wijesinghe, Meme
core  

Evidence of internal structure validity of the nursing outcome “Mechanical Ventilation Weaning Response: Adult (0412)” for critically ill COVID‐19 patients

International Journal of Nursing Knowledge, EarlyView.
Abstract Purpose To evaluate the evidence of internal structure validity of the nursing outcome (NO) “Mechanical Ventilation Weaning Response: Adult (0412)” of the NOs classification for critically ill COVID‐19 patients. Methods A methodological study focused on internal structural validation, part of a multicenter study, was carried out in the ...
Aline Batista Maurício, Viviane Martins da Silva, Agueda Maria Ruiz Zimmer Cavalcante, Larissa Giardini Bruni, Sue Ann Moorhead, Elizabeth Swanson, Karen Dunn Lopez, Marcos Venícios de Oliveira Lopes, Alba Lucia Bottura Leite de Barros   +8 more
wiley   +1 more source

Safer prehospital anaesthesia: updated guidelines from the Association of Anaesthetists

Anaesthesia, EarlyView.
Summary Introduction Prehospital emergency anaesthesia is recognised as a high‐risk clinical intervention. These updated guidelines consider changes in prehospital practice and parallel changes in the practice of in‐hospital emergency anaesthesia, with the aim of encouraging standardised safe anaesthetic practice in a challenging clinical area.
David Lockey, Celestine Weegenaar, Imran Ahmad, Pascale Avery, Philip Cowburn, Richard M. Lyon, Giles Nordmann, Andrew J. Pountney, Cosmo F. M. Scurr, Matthew D. Wiles   +9 more
wiley   +1 more source

Narrative Review on Therapies That Influence Inflammatory Responses During Extremely Premature Perinatal Respiratory Transition

Acta Paediatrica, EarlyView.
ABSTRACT Aims and Methods Advances in neonatal care have extended borderline survival to 22–24 post‐conceptional weeks. Present review discusses approaches for prolonging short pregnancies and prevention of serious morbidities in extremely premature infants born before 28 weeks of pregnancy.
Mikko Hallman
wiley   +1 more source

Budesonide and Surfactant Therapy Versus Surfactant Alone on Incidence of Lung Disease in Preterm Infants (BEST Lung): Study Protocol for a Systematic Review and Individual Participant Data Meta‐Analysis With Nested Prospective Meta‐Analysis

Acta Paediatrica, EarlyView.
ABSTRACT Introduction Bronchopulmonary dysplasia (BPD) is a leading cause of morbidity and mortality in preterm infants. Combining surfactant with budesonide has been proposed to prevent BPD, but results from existing randomised controlled trials (RCTs) are conflicting.
James X. Sotiropoulos, Brett J. Manley, Sol Libesman, Namasivayam Ambalavanan, Abhik Das, Christopher J. D. Mckinlay, Nalinikanta Panigrahy, Melinda Cruz, David Nguyen, Jonathan Williams, Peter Davis, Kylie E. Hunter, Anna Lene Seidler   +12 more
wiley   +1 more source

Using pulmonary gas exchange to estimate shunt and deadspace in lung disease: theoretical approach and practical basis.

J Appl Physiol (1985), 2022
Wagner PD, Malhotra A, Prisk GK.
europepmc   +1 more source

A novel alveolar Krebs cycle-triggered CO2 sensing mechanism regulates regional pulmonary ventilation.

, 2011
Pulmonary perfusion disorders provoke atelectasis in order to minimize ventilation/perfusion mismatch. However, the underlying mechanisms remain unknown.
Rainer Kiefmann, Martina Kiefmann, Leoni Schulte-Uentrop, Kai Heckel, Oliver Tritt, Sascha Tank, Alwin Goetz, Paula Keller   +7 more
core  

Effects of fentanyl overdose-induced muscle rigidity and dexmedetomidine on respiratory mechanics and pulmonary gas exchange in sedated rats.

J Appl Physiol (1985), 2022
Haouzi P, Tubbs N.
europepmc   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Integrating measurements of pulmonary gas exchange to answer clinically relevant questions. [PDF]

J Bras Pneumol, 2020
Neder JA, Berton DC, O'Donnell DE.
europepmc   +1 more source