Results 171 to 180 of about 1,640,993 (346)

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen, Rui Li, Yong She, Xuefei Liu, Yuanyang Huang, Yongling Ji, Keying Chen, Zhengbo Song, Runzhe Chen, Xuan Li, Qi Zhao, Qixun Chen, Ming Chen   +12 more
wiley   +1 more source

A case of plateau heart disease misdiagnosed as chronic pulmonary heart disease. [PDF]

J Hypertens
Zhang N, Tang F.
europepmc   +1 more source

Prevalence of Congenital Heart Disease-Related Pulmonary Arterial Hypertension Among The Children with Congenital Heart Disease Attending Follow-Up Clinic at Tash. Echocardiograph Diagnoses

, 2013
Lencho Gebi
openalex   +1 more source

Cardiac Catheterization in Children with Pulmonary Hypertensive Vascular Disease: Consensus Statement from the Pulmonary Vascular Research Institute, Pediatric and Congenital Heart Disease Task Forces

Pulmonary Circulation, 2016
M. J. Cerro, S. Moledina, S. Haworth, D. Ivy, M. A. Dabbagh, H. Banjar, Gabriel F Diaz, Alexandra Heath-Freudenthal, A. N. Galal, T. Humpl, S. Kulkarni, A. Lopes, A. Mocumbi, G. Puri, B. Rossouw, S. Harikrishnan, A. Saxena, Patience Udo, L. Caicedo, O. Tamimi, I. Adatia   +20 more
semanticscholar   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

Mechanistic gaps and statistical considerations in pulmonary heart disease: Insights from PAH combination therapy studies. [PDF]

ESC Heart Fail
Zhang Y.
europepmc   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

Significance of serum lncRNA XIST in chronic obstructive pulmonary disease and its progression to pulmonary heart disease. [PDF]

BMC Pulm Med
Huang X, Liang J, Li Y, Wei M, Liu Q, Jiang Y, Wang C, Ding J.   +7 more
europepmc   +1 more source

PULMONARY AND SYSTEMIC HEMODYNAMIC EFFECTS OF HYPERVENTILATION IN INFANTS AFTER REPAIR OF CONGENITAL HEART DISEASE [PDF]

, 1987
David Wessel, Paul R. Hickey, Dolly D. Hansen   +2 more
openalex   +1 more source