Results 111 to 120 of about 2,507 (209)

PDCD5 Contributes to Airway Epithelial Cell Damage via Mitochondrial Pathway and Participates in COPD Pathogenesis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan   +9 more
wiley   +1 more source

Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model

open access: yesInternational Journal of COPD, 2017
Xiaoyu Liu,1,* Cuiqing Ma,2,* Xiaoyu Wang,1 Wenjing Wang,1 Zhu Li,1 Xiansheng Wang,1 Pengyu Wang,1 Wuzhuang Sun,1 Baojian Xue3 1Department of Respiratory Medicine, The First Hospital of Hebei Medical University, 2Department of Immunology, Hebei Medical ...
Liu X   +8 more
doaj  

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen   +11 more
wiley   +1 more source

Triggering Receptor Expressed on Myeloid Cells‐2 Regulates Innate Lymphoid Cell Levels in Bleomycin‐Induced Pulmonary Fibrosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Idiopathic pulmonary fibrosis, a pathological change causing poor outcomes, is not reversible despite current antifibrotic therapy. Emerging evidence suggests that innate lymphoid cells (ILCs) mediate lung inflammation and fibrosis after stimulation by endogenous factors.
Hsiao‐Chin Shen   +7 more
wiley   +1 more source

Clinical Care Guideline Implementation of Nebulized Tranexamic Acid in Post‐Tonsillectomy Hemorrhage

open access: yesThe Laryngoscope, EarlyView.
In our quality initiative, we demonstrated how clinical care guidelines can be used as a strategy to implement tranexamic acid treatment of post‐tonsillectomy hemorrhage. High rates of algorithm adherence were observed with an associated reduction in need for operative control of hemorrhage.
Jennifer Lavin   +5 more
wiley   +1 more source

Safety Profile of Nebulized Ciprofloxacin‐Dexamethasone After Pediatric Airway Surgery

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objective To evaluate the safety profile and patterns of use of nebulized ciprofloxacin–dexamethasone (CPD) in pediatric patients undergoing airway surgery. Methods A retrospective chart review was performed of patients who underwent airway surgery at a tertiary pediatric center between 2019 and 2023 and received nebulized CPD 0.3%–0.1 ...
Abbey L. Landini   +8 more
wiley   +1 more source

A Randomized Single‐Center Proof of Principle Study to Evaluate the Effectiveness and Safety of a Hydrogel Laser Treatment Patch in Laser Hair Removal

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Laser hair removal (LHR) is a commonly performed aesthetic procedure known to generate a hazardous laser plume composed of toxic chemicals, ultrafine particles, and potentially infectious biological materials. Current mitigation strategies, such as smoke evacuation systems, are costly and often used inconsistently, highlighting the ...
Barry E. DiBernardo   +2 more
wiley   +1 more source

Voice and Speech in Atypical Parkinsonian Disorders

open access: yesMovement Disorders Clinical Practice, EarlyView.
Background Motor speech disorders are early, common, and functionally limiting features of atypical parkinsonian disorders (APDs) such as progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and multiple system atrophy (MSA). These impairments are underrecognized and undertreated in neurology clinics.
Federico Rodriguez‐Porcel   +48 more
wiley   +1 more source

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