Nanocrystals based pulmonary inhalation delivery system: advance and challenge [PDF]
Drug Delivery, 2022 Pulmonary inhalation administration is an ideal approach to locally treat lung disease and to achieve systemic administration for other diseases. However, the complex nature of the structural characteristics of the lungs often results in the difficulty ...
Pengfei Yue +7 more
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Pulmonary inhalation for disease treatment: Basic research and clinical translations [PDF]
Materials Today BioPulmonary drug delivery has the advantages of being rapid, efficient, and well-targeted, with few systemic side effects. In addition, it is non-invasive and has good patient compliance, making it a highly promising drug delivery mode. However, there have
Bin Wang +8 more
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Preserved Acute Pulmonary Endothelial Homeostasis with Hydrogen Gas Inhalation After Neonatal Hypoxia–Ischemia Despite Increased Neutrophil Accumulation [PDF]
BiomedicinesBackground/Objectives: Hydrogen gas (H2) inhalation has shown neuroprotective effects in neonatal hypoxic–ischemic models. However, its impact on pulmonary endothelial activation and respiratory function after hypoxic–ischemic insult remains unclear ...
Takayuki Yokota +14 more
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Development of a Controlled-Dose Aerosol Challenge Method Using a Lung Fluid Quantitative Nebulizer [PDF]
MicroorganismsAirborne transmission represents a primary route of influenza virus dissemination. In animal infection models, conventional intranasal instillation fails to recapitulate the physiological features of natural respiratory infection.
Mingjie Shao +6 more
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Improving the Inhalation Technique in Patients with Obstructive Pulmonary Diseases [PDF]
Journal of Biomedical & Clinical Research, 2016 The study aimed to assess the inhalation technique of patients with bronchial asthma/chronic obstructive pulmonary disease (COPD) via an objective method and to evaluate the effect of training in patients with incorrect technique.
Zlatina Ivanova +5 more
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Inhalation exposure to surrogate military burn pit emissions impairs systemic microvascular function: linking pulmonary insult and diverse peripheral responses [PDF]
Particle and Fibre ToxicologyMillions of U.S. troops and supporting personnel have been deployed to military bases in the Middle East. Essentially all personnel on military bases were exposed to the combustion emissions generated by open pit waste burning.
Van Nguyen +19 more
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The optimization of iloprost inhalation under moderate flow of oxygen therapy in severe pulmonary arterial hypertension [PDF]
Pulmonary Circulation, 2018 Inhaled iloprost efficiently improves pulmonary hemodynamics, exercise capacity, and quality of life in patients with pulmonary arterial hypertension (PAH). However, the process of inhalation is laborious for patients suffering from resting dyspnea.
Kazuhiko Nakayama +11 more
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Human re-inhalation ratio under typical conditions [PDF]
E3S Web of Conferences, 2022 Inhaled air quality is directly related to occupants’ health and quality of life. In this study, a numerical breathing thermal manikin was employed, who breathed following a sinusoidal function, with 10 breathing cycles per minute.
Zong Jie, Ai Zhengtao
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Journal of Medicine in Scientific Research, 2022 Introduction Pulmonary arterial hypertension (PH) is commonly found in patients with mitral valve diseases. Most of the drugs used for PH treatment are nonselective pulmonary vasodilators that may cause a modest decrease in pulmonary arterial pressure ...
Ahmed K. Abdel Ghany Hassan +4 more
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