Results 51 to 60 of about 682,316 (295)

Formulation pre-screening of inhalation powders using computational atom-atom systematic search method. [PDF]

, 2015
The synthonic modeling approach provides a molecule-centered understanding of the surface properties of crystals. It has been applied extensively to understand crystallization processes.
Jaffari, Sara, Soufian, Majeed, Roberts, Kevin J., Darragh Murnane (1348947), Soufian, M, Jaffari, S, Vasuki Ramachandran, Forbes, Ben, Elizabeth Collins, Jonathan Pickering, Ramachandran, V, Martin, GP, Robert B. Hammond (1348938), Klimentina Pencheva, Gary P. Martin (1348953), Collins, E, Vasuki Ramachandran (1348941), Collins, Elizabeth, Pencheva, K, Roberts, KJ, Elizabeth Collins (1348959), Klimentina Pencheva (1348962), Ben Forbes, Hammond, Robert B., Gary P. Martin, Pickering, Jonathan, Murnane, Darragh, Robert B. Hammond, Kevin J. Roberts (1348965), Ramachandran, Vasuki, Martin, Gary P., Jonathan Pickering (1348968), Kevin J. Roberts, Murnane, D, Sara Jaffari (1348956), Darragh Murnane, Sara Jaffari, Hammond, RB, Forbes, B, Majeed Soufian (1348944), Majeed Soufian, Pickering, J, Ben Forbes (1348950), Pencheva, Klimentina   +43 more
core   +1 more source

Application of [18F]FLT‐PET in pulmonary arterial hypertension: a clinical study in pulmonary arterial hypertension patients and unaffected bone morphogenetic protein receptor type 2 mutation carriers [PDF]

, 2021
Pulmonary arterial hypertension is a heterogeneous group of diseases characterized by vascular cell proliferation leading to pulmonary vascular remodelling and ultimately right heart failure. Previous data indicated that 3′‐deoxy‐3′‐[18F]‐fluorothymidine
Onno A. Spruijt, Jansen, Samara MA, Anton V. Noordegraaf, Botros, Liza, Liza Botros, Ashek, Ali, de Man, Frances S, Bogaard, Harm J., Marc C. Huisman, Tramper, Jelco, Spruijt, Onno A., Harms, Hans, Jelco Tramper, Samara M.A. Jansen, Jansen, Samara M. A., Hans Harms, Anton Vonk Noordegraaf, Harm J. Bogaard, de Man, Frances S., Bogaard, Harm J, Zhao, Lan, Aman, Jurjan, Ali Ashek, Frances S. de Man, Frances S. deMan, Noordegraaf, Anton V., Spruijt, Onno A, Huisman, Marc C., Huisman, Marc C, Lan Zhao, Noordegraaf, Anton, Jurjan Aman   +31 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Urinary Pharmacokinetic Methodology to Determine the Relative Lung Bioavailability of Inhaled Beclometasone [PDF]

Urinary pharmacokinetic methods have been introduced to identify the relative lung and systemic availability of inhaled drugs but have not been extended to corticosteroids.
Said, Amira
core   +3 more sources

Irritant Inhalation Evokes P Wave Morphological Changes in Spontaneously Hypertensive Rats via Reflex Modulation of the Autonomic Nervous System

Frontiers in Physiology, 2021
Irritant inhalation is associated with increased incidence of atrial fibrillation (AF) and stroke. Irritant inhalation acutely regulates cardiac function via autonomic reflexes.
J. Shane Hooper, Thomas E. Taylor-Clark
doaj   +1 more source

A statistical evaluation of the effects of gender differences in assessment of acute inhalation toxicity [PDF]

, 2011
Acute inhalation toxicity of chemicals has conventionally been assessed by the median lethal concentration (LC50) test (organisation for economic co-operation and development (OECD) TG 403).
Price, Charlotte, Indans, Ian, Creton, S, Griffiths, Diane, Guest, R, Edwards, P, Griffiths, David, Stallard, Nigel, Creton, Stuart, Stallard, N, Indans, I, Price, Charlotte L, Edwards, Philippa, Guest, Robert   +13 more
core   +1 more source

Inhalation studies with the Göttingen minipig

, 2022
S.249-259A method for inhalative exposure of minipigs to aerosols and gases has been developed. Minipigs are exposed via mask inhalation to the test substance using a computer-controlled exposure system that permits simultaneous exposure of groups of ...
Windt, H., Clausing, P., Walles, M., Borlak, J., Koch, W.   +4 more
core   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Inhaled NO and Pulmonary Vasodilation [PDF]

Circulation, 1998
To the Editor: Hare et al1 concluded that inhaled nitric oxide (NO) caused selective pulmonary vasodilation in patients receiving left ventricular assist device support and that this accounted for the increase in mean left atrial pressure, which they considered a beneficial hemodynamic effect.
openaire   +1 more source

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source