Results 61 to 70 of about 717,546 (265)

Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A‐Dependent CXCL5 Upregulation

open access: yesAdvanced Science, EarlyView.
HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun   +12 more
wiley   +1 more source

Computed Radiography of Pulmonary Nodules: Evaluation of Inflated-fixed Lung [PDF]

open access: yes, 1991
Authors photographed 16 inflated-fixed pulmonary nodules by using computed radiography (CR). The pixel value of both pulmonary nodule and normal lung was requid by data incorporated in CR, and its ratio was analyzed.
Nakanishi, Takashi   +2 more
core  

[Radiological evaluation of incidental pulmonary nodules]

open access: yes, 2013
Item does not contain fulltextSince the widespread use of computed tomography (CT), the detection of pulmonary nodules has considerably increased and has become part of the daily clinical routine. In the evaluation of pulmonary nodules, malignant nodules
Schaefer-Prokop, C.M., Prosch, H.
core   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin   +17 more
wiley   +1 more source

A CAD system for pulmonary nodule prediction based on deep three-dimensional convolutional neural networks and ensemble learning.

open access: yesPLoS ONE, 2019
BackgroundDetection of pulmonary nodules is an important aspect of an automatic detection system. Incomputer-aided diagnosis (CAD) systems, the ability to detect pulmonary nodules is highly important, which plays an important role in the diagnosis and ...
Wenkai Huang, Yihao Xue, Yu Wu
doaj   +1 more source

A neural network structure for detecting pseudo positive pulmonary nodules.

open access: yes, 2019
A neural network structure for detecting pseudo positive pulmonary nodules.
Yihao Xue (6948803)   +2 more
core   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Accuracy of pulmonary nodules segmentation.

open access: yes, 2015
APNSL: average pixels of segmented lesions; PNSLM: pixels in segmented lesions based on the manual; ONPMS: number of overlapping pixels with manual segmentation; SAR: accuracy of segmentation.Accuracy of pulmonary nodules segmentation.
Guohua Ji (436621)   +5 more
core   +1 more source

Versatile Co‐Engineering of Immunogenic Cell Death‐Primed Dead Tumor Cell Bodies With Tumor‐Activated MnO2 for cGAS‐STING‐Potentiated Personalized Immunotherapy

open access: yesAdvanced Science, EarlyView.
DTBEI@CS@MnO2, fabricated via modular electrostatic co‐engineering and photothermal/photodynamic immunogenic cell death, specifically responds to the acidic and GSH‐rich tumor microenvironment. This triggers the release of DTBEI that provides tumor antigens, DNA, and DAMPs, as well as the generation of Mn2+, thereby synergistically potentiating cGAS ...
Bolun Xu   +6 more
wiley   +1 more source

Primary Pulmonary Epithelioid Hemangioendothelioma: A Rare Cause of PET-Negative Pulmonary Nodules [PDF]

open access: yes, 2011
We report here a case of primary pulmonary epithelioid hemangioendothelioma diagnosed in a 67-year-old Caucasian man, presenting with exertion dyspnoea, dry cough, and multiple bilateral pulmonary nodules revealed by computed tomography.
Ravenna F.   +21 more
core   +3 more sources

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