Results 171 to 180 of about 21,029 (260)

Broadening horizons: Pathogenesis and therapeutics of renal ciliopathies

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
This review elucidates the molecular mechanisms and aberrant signaling pathways in renal ciliopathies, links genetic heterogeneity to clinical phenotypes, and lays a theoretical basis for prenatal diagnosis and novel therapies. Abstract Renal ciliopathies encompass a spectrum of genetic disorders arising from structural or functional impairments of ...
Qiaowei Zhang, Shuwen Xue, Zhi Gao, Panlai Shi, Li Wang, Qi Feng, Xiangdong Kong, Xiaofan Zhu   +7 more
wiley   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, Volume 2, Issue 3, September 2026.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Pulmonary Sequestration in Adults: Endovascular and Hybrid Treatment Strategies-A Systematic Review. [PDF]

J Clin Med
Szablics FÉ, Bérczi Á, Nyárády BB, Philippovich M, Szőnyi Á, Dósa E.   +5 more
europepmc   +1 more source

Dysregulated circRNA expression profile and associated miRNA sponging in abnormal lung development in congenital diaphragmatic hernia

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Circular RNAs (circRNAs) are stable, stage‐ and tissue‐specific regulators of gene expression warranting their study in abnormal fetal lung development in congenital diaphragmatic hernia (CDH). We present a CDH‐specific circRNA biosignature in the nitrofen rat model (E15/E21) using orthogonal validation with human comparison and discovered conserved ...
Marietta Jank, Arzu Ozturk Aptekmann, Rina Tanaka, Muntahi Mourin, Nolan De Leon, Matthew Kraljevic, Daywin Patel, Wai Hei Tse, Claire McCallum, Richard Wagner, Shana Kahnamoui, Yuichiro Miyake, Athanasios Zovoilis, Takashi Doi, Michael Boettcher, Richard LeDuc, Richard Keijzer   +16 more
wiley   +1 more source

Intralobar pulmonary sequestration coexisting with pulmonary cryptococcosis: A case report and literature review. [PDF]

Exp Ther Med
Cheng D, Wang Y, Li J, Yu D, Wang Y, Fan J, Wang J, He L.   +7 more
europepmc   +1 more source

Venetoclax for elderly patients with acute myeloid leukaemia unfit for intensive chemotherapy: Prospects, resistance mechanisms and management strategies

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Resistance to venetoclax has become a critical bottleneck limiting its long‐term clinical benefits. A thorough understanding of the underlying resistance mechanisms and the development of novel strategies to overcome resistance are central to improving survival outcomes in elderly AML patients. Abstract To date, the treatment of acute myeloid leukaemia
Jinlin Zhang, Jile Liu, Mohan Zhao, Xiaoyu Zhang, Linlin Liu, Mengnan Li, Changze Cao, Rui Zhang, Mingfeng Zhao   +8 more
wiley   +1 more source

Intrapericardial Extralobar Pulmonary Sequestration: A Case Report and Systematic Review of a Unique Embryologic Variant. [PDF]

J Clin Med
Roveri M, Pedroni G, Preziosi A, Arcieri L, Marianeschi S, Macchini F, Zanini A.   +6 more
europepmc   +1 more source

Current strategies to enhance the target efficiency of advanced multifunctional ultrasound contrast agents in ischemic diseases

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
The graphical abstract outlines a novel multifunctional ultrasound contrast agent for the diagnosis and treatment of ischemic diseases, along with innovative strategies to enhance its targeting efficiency. Abstract Ischemic diseases, such as myocardial infarction, stroke, and peripheral ischemia, are leading causes of death and disability worldwide ...
Yangyang Zhou, Jing Lin, Yu Chen, Jiaqi Zhao   +3 more
wiley   +1 more source

Robotic-assisted versus open resection of pulmonary sequestration: a retrospective cohort study. RATS surgery for pulmonary sequestration. [PDF]

Gen Thorac Cardiovasc Surg
Deissner H, Campisi A, Griffo R, Niedermaier B, Muley T, Allgäuer M, Winter H, Eichhorn ME.   +7 more
europepmc   +1 more source

Atmospheric Aerosol Neurotoxicity and Parkinson's Disease: Mechanisms and Perspectives

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Schematic overview of the pathways and pathological mechanisms connecting atmospheric aerosol exposure to PD. Atmospheric aerosols, including PM2.5 and nanometer/ultrafine particles loaded with metal particles, persistent organic pollutants (POPs), polycyclic aromatic hydrocarbons (PAHs) and dioxins, enter the body predominantly via pulmonary ...
Yitian Gao, Minxiang Dong, Chenyang Duan, Xiaohan Zheng, Liming Qu   +4 more
wiley   +1 more source