Results 101 to 110 of about 685,376 (295)

Human Fibroblast–Myeloid Cell Tissue Atlas Across the Lungs, Synovium, Skin, and Heart

Arthritis &Rheumatology, EarlyView.
Objective The availability of single‐cell RNA sequencing (scRNAseq) data in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald, Katerina Apostolopoulou, Olympia Hardy, Melpomeni Toitou, Gabriela Kania, Przemyslaw Blyszczuk, Raphael Micheroli, Thomas D. Otto, Mariola Kurowska‐Stolarska, Caroline Ospelt   +9 more
wiley   +1 more source

HECTD1-mediated SFTPB overexpression in fibrotic lung induced by silica

Biochemistry and Biophysics Reports
Alveolar epithelial cells type 2 are lung progenitor and secretory cells capable of secreting four surfactant proteins, namely surfactant protein A (SFTPA), surfactant protein B (SFTPB), surfactant protein C (SFTPC), and surfactant protein D (SFTPD ...
Mengling Chen, Shencun Fang
doaj   +1 more source

Comparative Transcriptional Profiling of Key Macrophage and Fibroblast Subpopulations in Rheumatoid Arthritis–Associated Lung Disease

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) often involves extra‐articular complications, including interstitial lung disease (ILD) and/or pulmonary nodules. Transcriptomic profiling of lung tissue provides the opportunity to directly assess cell‐specific gene expression and corresponding pathway activation in different types of rheumatoid lung disease ...
Tracy Tabib, Ogechukwu Ezenwa, Joshua Sciurba, Eleanor B. Valenzi, John Sembrat, Brittany Cody, Jishnu Das, Robert Lafyatis, Dana P. Ascherman   +8 more
wiley   +1 more source

Lung Ultrasound-Guided Surfactant Therapy in Neonatal Pneumothorax and Pulmonary Hemorrhage: Pathophysiology, Diagnostic Ultrasonography, and Emerging Clinical Approaches

Children
Background and Objectives: Lung ultrasound (LUS) has fundamentally transformed neonatal respiratory diagnostics, offering a radiation-free, bedside-applicable modality capable of guiding surfactant therapy, characterizing pulmonary pathology, and ...
Adina Mihaela Frenti, Florin Filip, Elena Tătăranu, Vlad Dima, Roxana Axinte, Alina Sânzâiana Melinte, Mirabela Dima, Iulia Ciubotariu, Petronela Vicoveanu, Smaranda-Ileana Jurchis-Irimie, Smaranda Diaconescu   +10 more
doaj   +1 more source

Use of therapeutic surfactant lavage in a preterm infant with massive pulmonary hemorrhage

Clinics and Practice, 2012
We report a case of a premature infant presenting with recurrent pulmonary hemorrhage in which we performed a therapeutic lavage with diluted surfactant after an acute episode of bleeding with severe intractable hypoxemia.
Ino Kanavaki, Laszlo Vutskits, Peter C. Rimensberger   +2 more
doaj   +1 more source

Plasma Proteome Reflects Tissue Damage and Clinical Manifestations in Patients With Inflammatory Myopathies

Arthritis &Rheumatology, EarlyView.
Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins.
Yue‐Bei Luo, Josefin Kenrick, Angeles S. Galindo‐Feria, Antonella Notarnicola, Ana Daniela Ulloa Navas, Irene Peralta‐Garcia, Orane Demuynck, Andrea Kemp, Valérie Leclair, Karin Lodin, Eveline Van Gompel, Lara Dani, Fabricio Espinosa‐Ortega, Maryam Dastmalchi, Leonid Padyukov, Charlotta Preger, María Bueno Álvez, Mathias Uhlén, Peter Nilsson, Fredrik Edfors, Lina‐Marcela Diaz‐Gallo, Elisa Pin, Ingrid E. Lundberg, Begum Horuluoglu   +23 more
wiley   +1 more source

Learning beyond the lab: A gamified approach to anatomy education in a museum‐based experience

Anatomical Sciences Education, EarlyView.
Abstract Anatomy education, traditionally rooted in descriptive instruction and cadaveric dissection, is undergoing a significant transformation through the integration of educational technologies and contemporary pedagogical strategies. Among these, active learning methodologies, such as gamified‐based learning, have emerged as approaches designed to ...
Wendell Nunes da Silva, Diego Pulzatto Cury, Silvia Lacchini, Ana Paula Cremasco Takano   +3 more
wiley   +1 more source

Video‐Assisted Intralesional Curettage for Invasive Nonmalignant Giant Cell Tumors

Arthroscopy Techniques, EarlyView.
Abstract Giant cell tumor of bone is a locally aggressive benign neoplasm with a strong tendency for local recurrence after surgical treatment. Intralesional excision and curettage is preferred in most cases to maximize tumor removal while preserving the affected joint.
George Loria, Mohamed Ahmed Mohamed, George Alexander Rublev, Irakli Gogua, Giorgi Zimlitski, Mikheil Zimlitski   +5 more
wiley   +1 more source

Exogenous surfactant for lung contusion causing ARDS: A systematic review of clinical and experimental reports

The Clinical Respiratory Journal
This systematic review aimed to summarize the available data on the treatment of pulmonary contusions with exogenous surfactants, determine whether this treatment benefits patients with severe pulmonary contusions, and evaluate the optimal type of ...
Tomáš Merkl, David Astapenko, Radek Štichhauer, Antonín Šafus, Tomáš Dušek, Jiří Kotek, David Řehák, Petr Lochman   +7 more
doaj   +1 more source

Hypobaric hypoxia-related impairment of pulmonary surfactant proteins A and D did not favour Pneumocystis carinii Frenkel 1999 growth in non-immunocompromised rats

Parasite, 2008
It has been suggested that patients with pulmonary surfactant impairment are more susceptible to Pneumocystis infection than healthy controls. Owing the fact that most patients with pulmonary surfactant impairment also suffer from hypoxia, we explored ...
Vives M.F., Caspar-Bauguil S., Aliouat E.M., Escamilla R., Perret B., Dei-Cas E., Prévost M.C.   +6 more
doaj   +1 more source