Results 131 to 140 of about 74,178 (294)

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, EarlyView.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

The Journal of Pathology, EarlyView.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper   +6 more
wiley   +1 more source

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Biophysical function of pulmonary surfactant in liquid ventilation. [PDF]

Biophys J, 2023
Li G, Xu X, Zuo YY.
europepmc   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Congestion, decongestion, renal function and diuretics in (ESC) heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 730-732, April 2025.
Jan Biegus, Piort Gajewski, Piotr Ponikowski   +2 more
wiley   +1 more source

The impact of regional, seasonal, and environmental factors on the sleep status of urban residents in China

Sleep Research, EarlyView.
Abstract Background Sleep quality is influenced by various environmental factors, yet their impact across different regions and seasons in China remains understudied. Objective This study evaluated how environmental factors affect sleep quality, duration, and disorders among Chinese urban residents in different regions and seasons.
Youyang Qu, Shuhan Meng, Wanqiao Qi, Guihai Chen, Zan Wang, Jinzhu Yan, Ping Gu, Yanmei Zhu, Zifen Wan, Li Wang, Yuanqing Wang, Zhongming He, Dali Li, Lisan Zhang, Yunhui Lv, Guohui Li, Weimin Qu, Lili Long, Weiping Liu, Ning Li, Jianbin Liu, Wei Wu, Xiaojiang Jiang, Liang Xie, Liying Deng, Xiang Gao, Zhili Huang, Yulan Zhu   +27 more
wiley   +1 more source

Molecular Impact of Conventional and Electronic Cigarettes on Pulmonary Surfactant. [PDF]

Int J Mol Sci, 2023
Garavaglia ML, Bodega F, Porta C, Milzani A, Sironi C, Dalle-Donne I.   +5 more
europepmc   +1 more source

Pulmonary surfactant therapy.

The Western journal of medicine, 1995
Surfactant replacement therapy is now an integral part of the care of neonates since several clinical trials of natural surfactant extracts and synthetic preparations have shown efficacy in the treatment of infants with hyaline membrane disease.
F R, Poulain, J A, Clements
openaire   +1 more source