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Editorial: Bronchopulmonary dysplasia: latest advances-volume II. [PDF]
Front PediatrPerveen S, Chen JY.
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Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11986-11989, December 2026.
Luke A. Ephraums +9 more
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New England Journal of Medicine, 1993
In 1959, not long after surfactant had been identified as critical to maintaining lung inflation at low transpulmonary pressures,1,2 Avery and Mead3 reported that saline extracts from the lungs of preterm infants with respiratory distress syndrome lacked the low surface tension characteristic of pulmonary surfactant. After several unsuccessful attempts
Alan H. Jobe, Alastair J J Wood
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In 1959, not long after surfactant had been identified as critical to maintaining lung inflation at low transpulmonary pressures,1,2 Avery and Mead3 reported that saline extracts from the lungs of preterm infants with respiratory distress syndrome lacked the low surface tension characteristic of pulmonary surfactant. After several unsuccessful attempts
Alan H. Jobe, Alastair J J Wood
exaly +3 more sources
Canadian Journal of Biochemistry and Cell Biology, 1984
The mammalian lung is stabilized by a specialized material, the pulmonary surfactant, which acts by reversibly reducing the surface tension at the air–liquid interface of the lung during breathing. Pulmonary surfactant contains approximately 90% lipid and 10% proteins. Dipalmitoyl phosphatidylcholine, the major lipid component, appears to be primarily
F, Possmayer +3 more
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The mammalian lung is stabilized by a specialized material, the pulmonary surfactant, which acts by reversibly reducing the surface tension at the air–liquid interface of the lung during breathing. Pulmonary surfactant contains approximately 90% lipid and 10% proteins. Dipalmitoyl phosphatidylcholine, the major lipid component, appears to be primarily
F, Possmayer +3 more
openaire +2 more sources
The Pulmonary Surfactant System
Hospital Practice, 1990Surfactant's importance is underscored by the severe morbidity of deficiency states--primary, as in neonatal respiratory distress syndrome, or secondary, as in ARDS. Current knowledge of surfactant synthesis and metabolism is reviewed. Clinically, the effectiveness of exogenous surfactant in RDS has prompted investigation of its administration in ARDS.
S P, Caminiti, S L, Young
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Pulmonary surfactant and tuberculosis
Tuberculosis, 2009Mycobacterium tuberculosis comes in contact with pulmonary surfactant, alveolar macrophages and type II epithelial cells. Alveolar type II epithelial cells secrete pulmonary surfactant, a complex mixture of phospholipids and proteins lining the alveolar surface, while alveolar macrophages are involved in surfactant catabolism.
Zissis C, Chroneos +3 more
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Biomimetic pulmonary surfactants
Life Sciences, 1994Considerable progress has been made in the development of defined mixtures of proteins or peptides with phospholipids which mimic the activity of natural pulmonary surfactants. Several of these biomimetic surfactants are active in animal models and clinical syndromes of surfactant deficiency.
L R, McLean, J E, Lewis
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