Results 221 to 230 of about 1,493,409 (315)

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, Volume 269, Issue 3, Page 268-283, July 2026.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source

Alveolar type 2 cell LRP1 is needed for surfactant phospholipid metabolism and pulmonary function in mice. [PDF]

J Lipid Res
Ward R, Krishnan SS, Stavrovskaya I, Sanchez-Gonzalez D, Agudelo CW, Park SS, Mai M, Cai H, Martinez J, Cox K, Rahman A, Kiang C, Campos-Azpiroz M, Geraghty P, Lopez-Rodriguez E, Area-Gomez E, Shmarakov I, Goldberg IJ, Foronjy RF, Garcia-Arcos I.   +19 more
europepmc   +1 more source

A Novel Low‐Cost Technique for Three‐Dimensional Cardiopulmonary Preservation Using Internal Poly(Vinyl Acetate) (PVAc) Injection

Anatomia, Histologia, Embryologia, Volume 55, Issue 4, July 2026.
ABSTRACT Anatomical preservation is essential for teaching and research; however, conventional formaldehyde‐based techniques present limitations due to toxicity, volatility and environmental impact. Plastination provides excellent morphological quality, but its high cost, reliance on flammable solvents and requirement for specialized equipment limit ...
Fabio Cesar Magioli Abdala, Silvio Pires Gomes, Silmara Santos Lazzaretti, Maria Clara Ucker Costódio, Bruno Cesar Schimming, Rinaldo José Ortiz, Vinicius Pedro Silva de Oliveira, Selma Maria Michelin Matheus, Tais Harumi de Castro Sasahara   +8 more
wiley   +1 more source

Pulmonary drug delivery of quercetin through scalable PEGylated mixed micelles of Gelucire® and Tetronic®. [PDF]

RSC Adv
Bhalani D, Pillai SA, Shukla A, Kharkwal G, Ray D, Aswal VK, Bahadur P.   +6 more
europepmc   +1 more source

High prevalence of loss of Claudin‐18 expression in invasive non‐mucinous lung adenocarcinoma: Potential diagnostic implications in routine practice

Histopathology, Volume 89, Issue 1, Page 81-97, July 2026.
Loss of Claudin‐18 (Cldn18) expression is a frequent and specific feature of non‐mucinous lung adenocarcinoma (NM‐LUAD). Cldn18 immunohistochemistry may serve as an ancillary tool for distinguishing malignant from non‐neoplastic alveolar epithelium, as well as for differentiating NM‐LUADs with mucin production from M‐LUADs, particularly in small or ...
Stefano Lucà, Marco Montella, Mario Fordellone, Riccardo Monti, Maria Giulia Disanto, Giuseppa Zannini, Marina Accardo, Maria Ali, Gaetano Di Guida, Carminia Maria Della Corte, Beatrice Leonardi, Severo Campione, Valerio Nardone, Floriana Morgillo, Alfonso Fiorelli, Luisella Righi, Mattia Barbareschi, Luka Brcic, Renato Franco   +18 more
wiley   +1 more source

How sighing regulates pulmonary surfactant structure and its role in breathing mechanics. [PDF]

Sci Adv
Novaes-Silva MC, Rodríguez-Hakim M, Thompson BR, Wagner NJ, Hermans E, Dupont LJ, Vermant J.   +6 more
europepmc   +1 more source

Shaping Ti3C2 MXene Nanospheres for Precision Near‐Infrared Photothermal Therapy

Advanced Functional Materials, Volume 36, Issue 46, 8 June 2026.
In this study, we report producing spherical MXenes via fs laser fragmentation of Ti3C2 flakes in liquid medium. The nanoparticles demonstrated pronounced light absorption and high photothermal conversion efficiencies of 68% and 63% under heating with NIR‐I and NIR‐II lasers, respectively.
Julia S. Babkova, Ivan V. Zelepukin, Konstantin G. Shevchenko, Gleb V. Tikhonowski, Lyubov V. Gorelik, Anton A. Popov, Anna S. Sogomonyan, Alina Yu. Kapitannikova, Ivan S. Kazantsev, Dmitry V. Dyubo, Daria A. Panova, Daniil I. Tselikov, Anton A. Minnekhanov, Aziz B. Mirkasymov, Georgy A. Ermolaev, Alexander V. Syuy, Gleb I. Tselikov, Aleksey V. Arsenin, Andrei V. Kabashin, Kostya S. Novoselov, Sergey M. Deyev, Valentyn S. Volkov   +21 more
wiley   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, Volume 36, Issue 44, 1 June 2026.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

[Pulmonary surfactant].

La Revue du praticien, 1980
M, Garrigues, A, Neidhart, J, Vanche
openaire   +3 more sources

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source