Results 251 to 260 of about 1,349,045 (346)

Autosomal Recessive Surfactant Metabolism Dysfunction Pulmonary III: A Clinical Case Report

Faizan Sadiq, Arooj Khan, Ali Nawaz, Syed Mohsin Ali Shah, Saba Khan   +4 more
openalex   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

The FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický, Sonja Lindfors, Saana Metso, Julia Koivula, Zoltan Szabo, Rasmus Valtonen, Mikko Tulppo, Johanna Magga, Samu Saarimäki, Sonja Bläuer, Ilkka Miinalainen, Risto Kerkelä, Petteri. T. Piepponen, Vootele Voikar, Juho Väänänen, Riikka Kivelä, Bhagwan Yadav, Hanna Lindgren, Pirkko Mattila, Fu‐Ping Zhang, Petra Sipilä, Reetta Hinttala, Satu Kuure   +22 more
wiley   +1 more source

Strategies to Enhance Nanocrystal Formulations for Overcoming Physiological Barriers Across Diverse Routes of Administration. [PDF]

Int J Nanomedicine
Yanamadala Y, Muthumula CMR, Khare S, Gokulan K.   +3 more
europepmc   +1 more source

Coarse-Grained Molecular Dynamics Study on Polyethylenimine-Based Nanoparticles for Pulmonary Gene Delivery: From Model Development to Surfactant Crossing Simulation

Hashemi, Seyedehniloofar
openalex   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

Nanoemulsion as a promising drug delivery strategy for effective eradication of Helicobacter pylori: current insights. [PDF]

Drug Deliv Transl Res
Saha M, Gupta A, Kunkalienkar S, Dhas N, Shetty S, Gupta A, Mutalik S, Krishnadas N, Chandrashekar R, Narasimhaswamy N, Moorkoth S.   +10 more
europepmc   +1 more source

Preparation and Characterization of Pulmonary Surfactant-Super Oxide Dismutase Liposomes

, 2009
Shazia Bashir, Abdul Manan, Mubashir Beigh, Abdul Hanan, Rajeev Sharma, Sheikh Irfan, Muhammad Amjad Bashir, M Resident, Rashid Mubashir   +8 more
openalex   +2 more sources

Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH signalling inhibitors

The FEBS Journal, EarlyView.
NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu, Haijiang Wang, Gunja Mishra, Lin‐Ting Wu, Chao Li, Maarten van Dinther, Jin Liu, Manuel A.F.V. Gonçalves, Peter ten Dijke, David A. Baker   +9 more
wiley   +1 more source

Functional Evaluation of Niosomes Utilizing Surfactants in Nanomedicine Applications. [PDF]

Int J Nanomedicine
Gao S, Sui Z, Jiang Q, Jiang Y.
europepmc   +1 more source

Caregivers' Experiences With Involuntary Oral Care for Individuals With Dementia Within the Dutch Care and Coercion Act

Gerodontology, EarlyView.
ABSTRACT Background Individuals with dementia frequently show care‐resistant behaviour toward the provision of oral care. Providing oral care despite care‐resistant behaviour is legally considered to be involuntary oral care. In the Netherlands, the provision of involuntary oral care to incapacitated individuals with dementia is regulated by the Care ...
Maud Jonker, Coos Engelsma, David J. Manton, Anita Visser   +3 more
wiley   +1 more source