Results 131 to 140 of about 1,109,394 (271)

In Vivo Comparison of Algorithms Estimating Left Ventricular Stroke Work From LVAD‐Derived Pump Parameters

Artificial Organs, EarlyView.
Our study validates non‐invasive stroke work estimation algorithms derived from LVAD pump parameters across preload reduction (inferior vena cava occlusion), afterload increase (aorta descendens occlusion), contractility increase (dobutamine infusion), and LVAD speed ramp interventions in 22 pigs.
Moriz A. Habigt, Marc Hein, Mare Mechelinck, Frederic Olbrich, Maike Stemmler, Alexander Schulz, Barbara Hammer, Sebastian Billig   +7 more
wiley   +1 more source

RLIM‐associated neurodevelopmental disorders: From clinical spectrum to molecular mechanisms

The FEBS Journal, EarlyView.
RLIM (RNF12) is an E3 ubiquitin ligase essential for mammalian development. Loss‐of‐function variants cause Tønne–Kalscheuer syndrome, while duplications cause Xq13 duplication syndrome, highlighting RLIM dosage sensitivity. This review summarizes the genetics, clinical features, and molecular mechanisms of RLIM‐associated disorders, integrating ...
Madison Landon, Kyra Swildens, Vera M. Kalscheuer, Cristina Gontan, Francisco Bustos   +4 more
wiley   +1 more source

High‐Intensity Interval Training Modulates NLRP3 Inflammasome‐Related Expression and Monocyte Subset Distribution in Adults With Obesity: A Randomised Trial

Immunology, EarlyView.
In sedentary adults with obesity, 8 weeks of high‐intensity interval training prevented the shift toward a pro‐inflammatory monocyte profile seen in nontrained controls—most robustly, a significantly lower proportion of intermediate monocytes at Week 8 (p = 0.014) while the control group also showed a within‐group rise in NLRP3 expression not observed ...
Daniela A. de Abreu, Ana Luíza P. A. Silveira, Stella de S. Vieira, Francisco A. H. Fonseca, Maria Cristina Izar, Jônatas B. do Amaral, Carolina N. França   +6 more
wiley   +1 more source

Comparative long-term results of surgery versus balloon valvuloplasty for pulmonary valve stenosis in infants and children.

, 2003
BACKGROUND: We compared the long-term results of surgical valvotomy (S) versus balloon valvuloplasty (BV) for pulmonary valve stenosis in infants and children. METHODS: Results after surgical pulmonary valvotomy (with concomitant ASD/VSD closure) (n = 62,
Peterson, C., Schilthuis, J.J., Bennink, G.B., Meijboom, E.J., Dodge-Khatami, A., Hitchcock, J.F., Johanneke J Schilthuis, Ali Dodge-Khatami, J.Francois Hitchcock, Claire Peterson, Ger B.W.E Bennink, Erik J Meijboom   +11 more
core   +1 more source

Characterization of AF Recurrence and Substrate Health by Electrographic Flow (EGF) Consistency in EGF Mapping

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Electrographic flow (EGF) mapping is an FDA 510(k)‐cleared method for visualizing atrial activation wavefronts in atrial fibrillation (AF). Its clinical efficacy in detecting AF sources was demonstrated in the FLOW‐AF randomized controlled trial, and the underlying machine learning strategy used to develop and refine EGF source ...
Steven Castellano, Marloes Jansen, Lucas V. A. Boersma, Marisa van der Graaf, Melissa H. Kong, Kostiantyn Ahapov, Philip Haeusser, Moritoshi Funasako, John D. Hummel, Wilber W. Su   +9 more
wiley   +1 more source

Cardiac structure and function in psoriasis: A cross‐sectional analysis of the PSOCADIA study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Individuals with well‐treated psoriasis exhibited a higher burden of myocardial dysfunction (GLS < 16%) compared with controls, independent of cardiometabolic comorbidity. The prevalence was similar across psoriasis severity, highlighting the importance of cardiovascular assessment in all patients with psoriasis. Abstract Background Psoriasis is linked
Maria Dons, Morten Sengeløv, Kristoffer Grundtvig Skaarup, Niklas Dyrby Johansen, Mats C. H. Lassen, Sofie Bøgh‐Sørensen, Filip Soeskov Davidovski, Julie Borchsenius, Peter Schnohr, Gorm Boje Jensen, Rasmus Møgelvang, Christoffer V. Nissen, Peter Riis Hansen, Brittany N. Weber, Claus Zachariae, Lone Skov, Tor Biering‐Sørensen   +16 more
wiley   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Congenital Pulmonary Valve Insufficiency [PDF]

, 2020
openaire   +1 more source

Pulmonary valve leaflet extension with bovine pericardium: for treatment of pulmonary insufficiency.

Texas Heart Institute journal, 2011
Using a homograft in a pulmonic area is sometimes inadvisable due to the lack of optimal graft materials. We report a case of pulmonary valve insufficiency that we treated by leaflet extension using the commercially available E-Leafcon template and bovine pericardium.
Tae Eun, Jung, Jong Hyun, Baek, Dong Hyup, Lee   +2 more
openaire   +1 more source