Results 81 to 90 of about 93,266 (264)

Estado da arte do procedimento percutâneo: paciente octogenário submetido com sucesso, em apenas uma sessão, a valvotomia pulmonar, implante de stent coronário e implante de marcapasso definitivo State of the art percutaneous procedure: octogenarian patient successfully submitted, in a single session, to a pulmonary valvotomy, coronary stent implant and permanent pacemaker implant

Arquivos Brasileiros de Cardiologia, 2005
É relatado caso de paciente de 82 anos, portador de insuficiência renal leve, estenose valvar pulmonar (EVP) severa, estenose severa de artéria descendente anterior e bloqueio atrioventricular total, submetido a angioplastia coronária com implante de ...
Wilson Albino Pimentel Filho, Milton de Macedo Soares Neto, Gil Vicente Cividanis, Rubens Vaz Feijó Júnior   +3 more
doaj   +1 more source

Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH signalling inhibitors

The FEBS Journal, EarlyView.
NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu, Haijiang Wang, Gunja Mishra, Lin‐Ting Wu, Chao Li, Maarten van Dinther, Jin Liu, Manuel A.F.V. Gonçalves, Peter ten Dijke, David A. Baker   +9 more
wiley   +1 more source

Predictors of Unfavourable Outcomes in Children and Adolescents Submitted to Surgical Mitral Valvuloplasty Secondary to Chronic Rheumatic Heart Disease

Arquivos Brasileiros de Cardiologia
Background: Mitral valve repair in paediatric patients with chronic rheumatic heart disease is superior to valve replacement and has been used with good results.
Renata Cristina Castro Cruz, Bruna Silva Cordeiro, Felipe de Souza Santos, Caroline Rodrigues Fernandes, Julia Maria Alves Gama, Ana Marice Teixeira Ladeia   +5 more
doaj   +1 more source

A rare situation in acute rheumatic carditis: Involvement of all four valves

The Turkish Journal of Pediatrics, 2017
Acute rheumatic fever continues to be an important health problem, especially in countries that are socioeconomically underdeveloped. Carditis, which develops in approximately half of the patients, is responsible for both early-stage mortality as well ...
Osman Güvenç, Derya Çimen
doaj   +1 more source

Comparative analysis of metabolic and functional cardiac alterations in diet‐ and genetically induced mouse models of cardiac dysfunction

The FEBS Journal, EarlyView.
Dietary and genetic stress trigger different routes to heart failure. In mice, a carbohydrate‐free high‐fat diet caused mitochondrial dysfunction and impaired energy production with preserved pumping function, while genetic obesity led to heart enlargement, fibrosis, and reduced function.
Christiane Ott, Patricia Baumgarten, Thorsten Henning, Daniela Weber, Iwona Wallach, Jana Grune, Ulrich Kintscher, Hermann‐Georg Holzhütter, Tilman Grune, Nikolaus Berndt   +9 more
wiley   +1 more source

Out With the Old, in With the New: Age‐Related D‐Dimer Thresholds

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background A fixed D‐dimer cut‐off threshold of 0.500 μg/mL is used in Blackrock Health Hermitage Clinic (BHHC) and most Haematology laboratories across Ireland, however, international guidelines have evolved over the past decade, and a growing body of evidence supports the use of age‐adjusted D‐dimer thresholds.
Ciara O'Connor, Claire McIntyre, Claire Wynne   +2 more
wiley   +1 more source

Long-Term Outcomes of Tetralogy of Fallot Repair with Pulmonary Valve Preservation and with Transannular Patch

Український журнал серцево-судинної хірургії
Introduction. Tetralogy of Fallot (ToF) is a prevalent cyanotic congenital heart defect, with surgical repair strategies focused on relieving right ventricular outflow tract obstruction (RVOTO).
Olga S. Borodinova, Anzhelika O. Mykhailovska   +1 more
doaj   +1 more source

Pulmonary Valve Replacement Using an Intraoperatively Created Trileaflet Autologous Pericardial Valve: A Case Series [PDF]

Iranian Journal of Medical Sciences
Background: Pulmonary valve replacement is inevitable for the majority of patients with long-standing pulmonary regurgitation. The purpose of this study was to describe the experience of employing a novel technique to create an intraoperatively handmade ...
Ahmad Ali Amirghofran, Kamran Jamshidi, Mohammadreza Edraki, Gholamhossein Ajami, Hamid Amoozgar, Mohammadreza Sabri, Hamid Arabi, Elahe Nirooie, Mohammad Kasaie, Rahim Hemmati, Mina Amiri   +10 more
doaj   +1 more source

Tandem Approach for Transvenous Lead Extraction: Efficacy, Safety, and Operational Learning Curve

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background and Aims The need for transvenous lead extraction (TLE) is rising due to increased cardiovascular device implantation and an aging population. While the superior access is standard, complex cases may benefit from the Tandem approach, combining femoral and superior access to improve efficacy and safety.
Alessio Petrone, Zaki Akhtar, Christos Kontogiannis, Viral Sagar, Jaspal Singh Gill, Lisa W.M. Leung, Zia Zuberi, Manav Sohal, Mark M. Gallagher   +8 more
wiley   +1 more source