Results 201 to 210 of about 1,817,394 (413)

Involvement of the Na+/Ca2+ Exchanger in the Automaticity of Guinea-Pig Pulmonary Vein Myocardium as Revealed by SEA0400

open access: yesJournal of Pharmacological Sciences, 2009
.: We examined the involvement of the Na+/Ca2+ exchanger in the automaticity of the pulmonary vein myocardium with a specific inhibitor, SEA0400. Action potentials were recorded from the myocardial layer of isolated guinea-pig pulmonary vein preparations,
Iyuki Namekata   +9 more
doaj  

A pH‐Sensitive Nanosized Covalent–Organic Polymer for Enhanced Tumor Photodynamic Immunotherapy by Hypoxia Relief and STAT3 Inhibition

open access: yesAdvanced Science, EarlyView.
The nanosized covalent organic polymer composed of photosensitizer porphyrin, pyruvate kinase inhibitor vitamin K3, and STAT3 inhibitor WP1066 is prepared for enhanced photodynamic immunotherapy by simultaneous hypoxia relief and STAT3 inhibition. Abstract Photodynamic therapy (PDT) is a promising cancer therapy modality by generating reactive oxygen ...
Lei Lei   +7 more
wiley   +1 more source

Clinical and Procedural Effects of Transitioning to Contact Force Guided Ablation for Atrial Fibrillation. [PDF]

open access: yes, 2019
Background: A major innovation in atrial fibrillation (AF) ablation has been the introduction of contact force (CF) sensing catheters. Objective: To evaluate procedural and clinical effects of transitioning to CF-guided AF ablation.
Dikdan, Sean J., Frisch, Daniel R.
core   +1 more source

Risk Factors and Predictive Models for Sarcopenia in Older Adults

open access: yesAGING MEDICINE, EarlyView.
Independent risk factors for sarcopenia identified by Lasso regression and logistic regression in the study were BMI, prealbumin, albumin/globulin ratio (A/G ratio), serum creatinine, and phosphorus. These factors were used to construct a nomogram model and a decision tree model. Both models showed effectiveness in predicting sarcopenia in older adults,
Shiyuan Zhang   +9 more
wiley   +1 more source

Survival benefit of adjuvant therapy completion with early initiation for patients with pancreatic ductal adenocarcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Adjuvant completion with early initiation may contribute to the improved survival of patients with pancreatic ductal adenocarcinoma. Abstract Aim To evaluate the prognostic effect of initiation timing and completion of adjuvant therapy in patients with pancreatic ductal adenocarcinoma.
Kenjiro Okada   +9 more
wiley   +1 more source

Short‐term outcomes of intracorporeal anastomosis in laparoscopic colectomy for colon cancer: A nationwide, multi‐institutional cohort study in Japan (ICAN study)

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
We retrospectively compared intracorporeal and extracorporeal anastomosis in patients undergoing laparoscopic colectomy for colon cancer in 46 institutions by using propensity‐score matching. Intracorporeal anastomosis showed advantages over extracorporeal anastomosis in terms of blood loss, intraoperative vascular injury, bowel recovery, and length of
Tomohiro Yamaguchi   +92 more
wiley   +1 more source

Impact of primary tumor clinicopathological factors on prognosis after hepatic resection for rectal liver metastases

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This retrospective study evaluates the prognostic factors in patients undergoing curative hepatic resection for rectal cancer liver metastases. It identifies lateral lymph node metastasis and perineural invasion as significant prognostic factors. Moreover, patients with these factors required nonsurgical treatment in the early postoperative period ...
Tomofumi Uotani   +9 more
wiley   +1 more source

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