Results 201 to 210 of about 180,777 (427)

Simple pulmonary vein isolation for atrial fibrillation [PDF]

open access: bronze, 2002
Renato A. K. Kalil   +1 more
openalex   +1 more source

Restoring Tumor Cell Immunogenicity Through Ion‐Assisted p53 mRNA Domestication for Enhanced In Situ Cancer Vaccination Effect

open access: yesAdvanced Science, Volume 12, Issue 14, April 10, 2025.
PRIZE, a P53‐repair nanosystem based on a virus‐mimicking nanostructure, delivers p53 mRNA into tumor cells, restoring P53 levels and enhancing immunogenicity. Its biomineralized structure stabilizes the mRNA, prolongs P53's half‐life, and precisely targets tumors.
Yan Liang   +10 more
wiley   +1 more source

Optimization of Lipid Nanoparticles with Robust Efficiency for the Delivery of Protein Therapeutics to Augment Cancer Immunotherapy

open access: yesAdvanced Science, Volume 12, Issue 17, May 8, 2025.
This study develops lipid nanoparticles (LNPs) combining cationic and ionizable lipids for efficient cytosolic protein delivery. Optimized LNPs deliver functional proteins, including antibodies, enzymes, and Cas9, with high serum stability and albumin‐mediated endocytosis.
Lanfang Ren   +6 more
wiley   +1 more source

A Universal and Versatile Zwitterionic Coating for Blood‐Contacting Catheters with Long Lengths and Complex Geometries

open access: yesAdvanced Science, EarlyView.
A universal and versatile zwitterion coating strategy is developed for blood‐contacting catheters with long lengths and complex geometries. The coating exhibits near‐zero fouling, superior anticoagulation, and selective biocapturing properties while maintaining excellent stability under dynamic blood flow.
Tong Zhang   +6 more
wiley   +1 more source

Is Pulmonary Vein Isolation Necessary for Curing Atrial Fibrillation? [PDF]

open access: bronze, 2003
Giuseppe Stabile   +5 more
openalex   +1 more source

A pH‐Sensitive Nanosized Covalent–Organic Polymer for Enhanced Tumor Photodynamic Immunotherapy by Hypoxia Relief and STAT3 Inhibition

open access: yesAdvanced Science, EarlyView.
The nanosized covalent organic polymer composed of photosensitizer porphyrin, pyruvate kinase inhibitor vitamin K3, and STAT3 inhibitor WP1066 is prepared for enhanced photodynamic immunotherapy by simultaneous hypoxia relief and STAT3 inhibition. Abstract Photodynamic therapy (PDT) is a promising cancer therapy modality by generating reactive oxygen ...
Lei Lei   +7 more
wiley   +1 more source

The usefulness of ventricular pacing during atrial fibrillation ablation in a persistent left superior vena cava: A case report

open access: yesIndian Pacing and Electrophysiology Journal, 2018
A 69-year-old woman with palpitations was referred to our hospital for a second session of atrial fibrillation (AF) catheter ablation. She had a history of AF ablation including pulmonary vein (PV) isolation and persistent left superior vena cava (PLSVC)
Sen Matsumoto   +3 more
doaj  

Prognostic value of surgical treatment in elderly patients with ulcerative colitis‐associated colorectal cancer: A subanalysis of a nationwide Japanese multicenter study

open access: yesAnnals of Gastroenterological Surgery, Volume 9, Issue 3, Page 486-495, May 2025.
Our study examined the characteristics of elderly patients diagnosed with ulcerative colitis‐associated colorectal cancer. We showed that factors associated with aggressive tumor characteristics played a significant role in recurrence risk in the nonelderly patients, but not in the elderly patients.
Kinuko Nagayoshi   +10 more
wiley   +1 more source

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