Results 81 to 90 of about 159,526 (403)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Electro-anatomical mapping of the left atrium before and after cryothermal balloon isolation of the pulmonary veins [PDF]

, 2009
Introduction: The 28 mm cryoballoon catheter is a device used for pulmonary vein isolation (PVI). The aim of this study was to evaluate the extent of the ablation in the antral regions of the left atrium.
Belle, Y. (Yves) van, Janse, P. (Petter), Jessurun, E., Jordaens, L.J.L.M. (Luc), Knops, S.P. (Simon), Rivero-Ayerza, M. (Maximo), Szili-Török, T. (Tamás)   +6 more
core   +4 more sources

Preventing atrial fibrillation by combined right isthmus ablation and cryoballoon pulmonary vein isolation in patients with typical atrial flutter: PAF‐CRIOBLAF study

Journal of Arrhythmia, 2021
Background Although less common, typical atrial flutter shares similar pathophysiological roots with atrial fibrillation. Following successful cavo‐tricuspid isthmus ablation using radiofrequency, many patients, however, develop atrial fibrillation in ...
Frédéric Anselme, Arnaud Savouré, Nicolas Clémenty, Olivier Cesari, Dominique Pavin, Laurence Jesel, Pascal Defaye, Serge Boveda, Philippe Rivat, Jacques Mansourati, Alexis Mechulan, Jean‐Pierre Cebron, Gilles Lande, Michael Bubenheim ScD, Antoine Milhem   +14 more
doaj   +1 more source

Expression of mRNA for phospholipase A(2), cyclooxygenases, and lipoxygenases in cultured human umbilical vascular endothelial and smooth muscle cells and in biopsies from umbilical arteries and veins [PDF]

, 1998
Arachidonic acid (AA) is released by phospholipase A(2) (PLA(2)) and then converted into vasoactive and inflammatory eicosanoids by cyclooxygenases (COX) and lipoxygenases (LOX).
Carlsson, Maria, Gidlöf, Anders, Sirsjö, Allan, Söderkvist, Peter, Uhl, Eberhard, Öst, Martin   +5 more
core   +1 more source

Cooling or Warming the Esophagus to Reduce Esophageal Injury During Left Atrial Ablation in the Treatment of Atrial Fibrillation. [PDF]

, 2020
Ablation of the left atrium using either radiofrequency (RF) or cryothermal energy is an effective treatment for atrial fibrillation (AF) and is the most frequent type of cardiac ablation procedure performed. Although generally safe, collateral injury to
Arnold, M, Campos, B, Clark, B, Feher, M, Gallagher, MM, Guerra, JM, Hayat, J, Kulstad, E, Leung, LWM, MacGregor, J, Mazur, A, Metzl, M, Nazari, J, Santangeli, P, Sharkoski, T, Tschabrunn, C, Zagrodzky, J   +16 more
core   +1 more source

Procedural efficacy and safety of standardized, ablation index guided fixed 50 W high‐power short‐duration pulmonary vein isolation and substrate modification using the CLOSE protocol

Cardiovascular Electrophysiology, 2021
Ablation index (AI)‐guided ablation according to the CLOSE protocol is very effective in terms of chronic pulmonary vein isolation (PVI). However, the optimal radiofrequency (RF) power remains controversial. Here, we thought to investigate the efficiency
A. Francke, Nadja Taha, F. Scharfe, S. Schoen, C. Wunderlich, M. Christoph   +5 more
semanticscholar   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Short- and long-term experience in pulmonary vein segmental ostial ablation for paroxysmal atrial fibrillation* [PDF]

, 2006
Introduction: Segmental ostial pulmonary vein isolation (PVI) is considered a potentially curative therapeutic approach in the treatment of paroxysmal atrial fibrillation (PAF).
Aichinger, J, Janssen, J, Martinek, M, Nesser, H.J, Pürerfellner, H   +4 more
core   +1 more source

Electrophysiological evaluation of pulmonary vein isolation [PDF]

Europace, 2009
Electrophysiologically demonstrated complete conduction block at the level of the veno-atrial junction is preferable as the endpoint of pulmonary vein (PV) ablation rather than circumferential periostial radiofrequency delivery. Knowledge of the individual anatomy of the PVs and the left atrium (LA), appropriate positioning of circular mapping ...
openaire   +2 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source