Results 81 to 90 of about 1,501,462 (300)

Paroxysmal atrial fibrillation ablation: Achieving permanent pulmonary vein isolation by point-by-point radiofrequency lesions

, 2017
Pulmonary vein isolation by point-by-point radiofrequency catheter ablation constitutes the cornerstone of catheter ablation strategies for the treatment of atrial fibrillation.
Frutos-López, Manuel, Arana-Rueda, Eduardo, Beatriz Jáuregui-Garrido, Eduardo Arana-Rueda, Alonso Pedrote, Manuel Frutos-López, Acosta, Juan, Juan Acosta, Pedrote, Alonso, Jáuregui-Garrido, Beatriz   +9 more
core   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Three cases of vasospastic angina following catheter ablation of atrial fibrillation

Journal of Arrhythmia, 2017
Pulmonary vein isolation is an effective treatment for patients with atrial fibrillation (AF).Although vasospastic angina (VSA) is not a common complication after ablation of AF, we report 3 cases of VSA following ablation of persistent AF.
Yoshihiko Kagawa, Eitaro Fujii, Satoshi Fujita, Norikazu Yamada, Masaaki Ito   +4 more
doaj   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Cardiac parasympathetic modulation in the setting of radiofrequency ablation for atrial fibrillation

Archives of Medical Science, 2019
The cardiac autonomic nervous system plays an important role in the genesis and maintenance of atrial fibrillation. Although, pulmonary vein isolation is the cornerstone in today’s approach to atrial fibrillation ablation, a considerable proportion of ...
Thiago G. Osório, Gaetano Paparella, Sebastian Stec, Gian Battista Chierchia, Carlo de Asmundis   +4 more
doaj   +1 more source

Imaging approaches for pulmonary vein isolation in patients after lobectomy or pneumonectomy: a case series

, 2023
Background In patients who underwent pneumonectomy, pulmonary vein isolation for atrial fibrillation by catheter ablation may be complicated by the anatomical alterations caused by the surgical intervention. Pre- and peri-procedural imaging can visualize
Rahm, Ann Kathrin, Rahm, A.K., Gang, Uffe Jakob Ortved, Gang, U.J.O., Linz, D., Linz, Dominik, Ann-Kathrin Rahm, Rahm, Ann-Kathrin, Dominik Linz, Uffe Jakob Ortved Gang   +9 more
core   +1 more source

An Optimized Freeze‐Dry Multimodal Workflow for Sequential Micro‐CT Imaging, Histology, and Molecular Profiling: A Use Case in Human Liver Fibrosis

Advanced Science, EarlyView.
Optimized freeze‐drying and eosin staining deliver artifact‐free micro‐CT images of liver tissue at near‐histological detail, then hand the same specimen back for sectioning, staining, and sequencing. Fibrotic volume distinguishes normal liver from cirrhosis, while preserved RNA reveals inflammatory gene upregulation—one biopsy, three dimensions, and a
Kristijan Skok, Laura Činč Ćurić, Jernej Vajda, Silvia Schauer, Martin Wagner, Rudolf Stauber, Carolin Lackner, Karl Kashofer, Markus Plass, Giovanny Rodriguez Blanco, Ian R. Wanless, Uroš Maver, Katrin Panzitt, Boštjan Vihar   +13 more
wiley   +1 more source

Adenosine following pulmonary vein isolation to target dormant conduction elimination (ADVICE): methods and rationale

, 2012
Pulmonary vein (PV) isolation (PVI) has emerged as an effective therapy for paroxysmal atrial fibrillation (AF). However, AF recurs in up to 50% of patients, generally because of recovery of PV conduction. Adenosine given during the initial procedure may
Guerra, Peter G, Thibault, Bernard, Talajic, Mario, Nattel, Stanley, Khairy, Paul, Novak, Paul, Dubuc, Marc, Skanes, Allan, ADVICE Study Investigators, Macle, Laurent, Puererfellner, Helmut, Verma, Atul, Jaïs, Pierre, Khaykin, Yaariv, Arentz, Thomas, Veenhuyzen, George, Scavée, Christophe, Guerra, Peter G., Weerasooriya, Rukshen, Rivard, Lena, Willems, Stephan, Roy, Denis   +21 more
core   +1 more source

Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure

Advanced Science, EarlyView.
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye, Jiamin Wu, Zixin Wu, Xi Liu, Jiajia Luo, Leyi Yang, Peng Shi   +6 more
wiley   +1 more source

Concurrent assessment of time-to-isolation and temperature at 30 s as an innovative metric for predicting the persistence of pulmonary vein isolation using second-generation cryoballoons

Journal of Cardiothoracic Surgery
Background We attempted to establish correlations between intraoperative variables such as time-to-isolation (TTI) and temperature (T) at the 30-second mark, and the sustained efficacy of pulmonary vein isolation.
Mei-Qiong Wu, Lin Chen, Liang-Hua Lian, Jian-Quan Chen, Yi-Ming Peng, Xue-Wen Liao, Ya-Zhou Lin, Jian-Cheng Zhang   +7 more
doaj   +1 more source