Results 141 to 150 of about 37,471 (196)

Acute intrapartum deep venous thrombosis: A case report

open access: yes
International Journal of Gynecology &Obstetrics, Volume 174, Issue 3, Page 1680-1682, September 2026.
Faith Arimoro   +2 more
wiley   +1 more source

Hydroxyurea (hydroxycarbamide) use in adults with haemoglobin SC disease: A real‐world study in Quebec

open access: yesBritish Journal of Haematology, Volume 209, Issue 3, Page 1291-1300, September 2026.
Summary Haemoglobin SC (HbSC) disease is the second most prevalent form of sickle cell disease, but evidence for hydroxyurea (hydroxycarbamide; HU) to prevent pain episodes was limited until the prospective identification of variables as outcomes for treatment (PIVOT) trial.
Alice Girard   +10 more
wiley   +1 more source

Agonist‐specific conformational dynamics at the β2‐adrenoceptor dictate allosteric modulation of Gαs signalling and bronchodilation

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 17, Page 5315-5335, September 2026.
Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah   +7 more
wiley   +1 more source

Microvascular dysfunction in chronic kidney disease: A feasibility study

open access: yesClinical Physiology and Functional Imaging, Volume 46, Issue 5, September 2026.
Abstract Background Microvascular dysfunction contributes to PAD progression, and its detection may facilitate earlier recognition and risk stratification. People with advanced chronic kidney disease (CKD) have a high burden of PAD, yet early detection is limited by disease‐related changes, such as medial calcification. Near‐infrared spectroscopy (NIRS)
Eli Bok   +6 more
wiley   +1 more source

Cancer survivorship in malignant melanoma

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 9, Page e1291-e1308, September 2026.
Summary Robust long‐term survival data have transformed the prognosis of metastatic melanoma. For combination therapy with immune checkpoint inhibitors (ICIs), 10‐year melanoma‐specific survival rates now exceed 50 %, and durable disease control is achievable in a substantial proportion of patients, including those with brain metastases.
Markus Reitmajer   +15 more
wiley   +1 more source

Non‐Invasive Assessment of Endothelial Dysfunction and Arterial Stiffness in Fontan Circulation

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 9, September 2026.
The Fontan procedure is the definitive treatment for complex congenital heart disease, creating a circulation without a subpulmonary ventricle. This altered hemodynamic state negatively affects endothelial function, contributing to progressive organ dysfunction and long‐term morbidity.
Amalia Baroutidou   +5 more
wiley   +1 more source

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