Results 51 to 60 of about 54,479 (292)

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction (REDUCE LAP-HF I [Reduce Elevated Left Atrial Pressure in Patients With Heart Failure]): A phase 2, randomized, sham-controlled trial [PDF]

, 2018
Background -In non-randomized, open-label studies, a transcatheter interatrial shunt device (IASD, Corvia Medical) was associated with lower pulmonary capillary wedge pressure (PCWP), less symptoms, and greater quality of life and exercise capacity in ...
Basuray, Anupam, Burkhoff, Daniel, Fail, Peter S., Feldman, Ted, Forde-McLean, Rhondalyn, Hummel, Scott L., Kahwash, Rami, Kaye, David M., Lilly, Scott, Litwin, Sheldon, Massaro, Joseph M., Mauri, Laura, Nielsen, Christopher D., Penicka, Martin, Petrie, Mark C., Ricciardi, Mark J., Shah, Sanjiv J., van der Harst, Pim   +17 more
core   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Persistent Oxygen Requirement beyond Prematurity: A Case of Acquired Pulmonary Vein Stenosis

Case Reports in Pediatrics, 2017
Acquired pulmonary vein stenosis is a rare cardiac defect and diagnosis can often be challenging, as many cases present with refractory or prolonged oxygen requirement over the expected course.
Tyler A. Fick, Bernadette Richards, Carl H. Backes, Molly K. Ball   +3 more
doaj   +1 more source

Congenital and Acquired Pulmonary Vein Stenosis [PDF]

Circulation, 2007
Pulmonary vein stenosis is a fascinating yet frustrating and difficult to manage condition with an exceptionally high mortality rate. Until recently, the disease was seen almost exclusively in young children with or without various forms of congenital heart disease. Pulmonary vein stenosis is a relatively rare condition.
Larry A, Latson, Lourdes R, Prieto
openaire   +2 more sources

“Intrapericardial Approach” for Venous Outflow Reconstruction in Living‐Donor Liver Transplantation for Budd‐Chiari Syndrome: Surgical Techniques and LongTerm Outcomes

Annals of Gastroenterological Surgery, EarlyView.
Unlike deceased‐donor liver transplantation, living‐donor liver transplantation (LDLT) for Budd‐Chiari Syndrome (BCS) presents distinctive challenges in hepatic venous (HV)‐outflow reconstruction because diseased HV–inferior vena cava (IVC) cannot be entirely replaced with healthy donor vessels.
Koichiro Hata, Tetsuya Tajima, Satoshi Ogiso, Shinji Uemoto, Etsuro Hatano   +4 more
wiley   +1 more source

Case report of the successful treatment of a rare complication of pulmonary vein stenting: atrial rupture and stent detachment

BMC Pulmonary Medicine
Pulmonary vein stenosis (PVS) is a relatively rare pulmonary vascular disease in clinical practice, and radiofrequency ablation (RFA) is a common cause of pulmonary vein stenosis.
Yu wei, Qin wei, Zhu ziyang, Li fajiu
doaj   +1 more source

What went wrong? The flawed concept of cerebrospinal venous insufficiency [PDF]

, 2013
In 2006, Zamboni reintroduced the concept that chronic impaired venous outflow of the central nervous system is associated with multiple sclerosis (MS), coining the term of chronic cerebrospinal venous insufficiency ('CCSVI'). The diagnosis of 'CCSVI' is
Al-Omari MH, Alikhani K, Bartomolei I, Batson OV, Baumgartner RW, Benabid AL, Doepp F, Eckenhoff JE, Hempel KJ, Hojnacki D, Kipshidze N, Kostecki J, Lang J, Lang J, Ludyga T, Malagoni AM, Masuhr F, Mayer C, Nicolaides AB, Oberwahrenbrock T, Odake G, Oktar SO, Salvi F   +22 more
core   +2 more sources

Extrapulmonic Stenosis of the Pulmonary Veins [PDF]

Circulation, 1959
A case is reported of a 6-year-old boy who had developed pulmonary hypertension because of obstruction to the pulmonary venous flow by severe stenosis of the pulmonary veins at their junction with the left atrium. The development of collateral circulation through the bronchial vessels led to early, severe hemoptysis.
J, BERNSTEIN, A C, NOLKE, J O, REED
openaire   +2 more sources

Implementation of First‐Line Rapid Genome Sequencing for Children in Pediatric and Cardiac Intensive Care Units

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Substantial data supports the use of rapid exome and genome sequencing (rES/rGS) in Neonatal Intensive Care Units (NICU), but fewer studies have examined the impact of rES/rGS in other pediatric critical care units. We evaluated the impact on diagnostic yield and time to diagnosis following a single‐center hospital policy change allowing ...
Alexandra C. Keefe, Abbey A. Scott, Lukas Kruidenier, Jessie Conta, Darci L. Sternen, Sarah V. Clowes Candadai, Shannon M. Stasi, Julia Parish‐Morris, Megan Sikes, Margaret P. Adam, Anita E. Beck, Jennifer C. Hayek, Ian Glass, James T. Bennett, Ghayda Mirzaa, Paul Kruszka, Britt Johnson, Kirsty McWalter, Deborah Copenheaver, Bethany Friedman, Michael Bamshad, Katrina M. Dipple, Tara L. Wenger   +22 more
wiley   +1 more source