Results 201 to 210 of about 143,581 (292)
Postoperative Care and Management in Pediatric Hematology‐Oncology Patients
European Journal of Haematology, EarlyView.ABSTRACT Pediatric patients with hematologic and oncologic diseases often undergo surgical procedures as part of diagnosis and therapy. These include central venous catheter placements, tumor resections, lymph node and bone marrow biopsies, among others.
Shachi Srivatsa, Sara A. Mansfield
wiley +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Background Platelet transfusion is commonly used to reduce bleeding risk in platelet consumptive disorders. However, platelets may also promote thromboinflammatory pathways, and contemporary data evaluating the association between platelet transfusion, thrombosis, and mortality in this population are limited.
Manas Pustake +6 more
wiley +1 more source
Harnessing Polygenic Risk Scores to Refine Venous Thromboembolism Risk Stratification
European Journal of Haematology, EarlyView.ABSTRACT Background Venous thromboembolism (VTE) is a major cause of morbidity in patients of all ages. Despite growing interest in polygenic risk scores (PRS) for VTE, their utility remains understudied. Our objective was to evaluate the independent impact of a PRS on VTE susceptibility in adults and children.
Katlyn G. McKay +7 more
wiley +1 more source
An update on the landscape of collagen bioactive fragments
The FEBS Journal, EarlyView.The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley +1 more source
Performing Large‐Scale Genetic Analysis in the Bleeding Disorders Community
Haemophilia, EarlyView.ABSTRACT Inherited bleeding disorders encompass a diverse group of conditions caused by genetic defects affecting coagulation factors, fibrinogen, von Willebrand factor, or platelet function. Despite major advances in quantitative and functional laboratory assays, a substantial diagnostic gap remains, particularly in patients with mild or atypical ...
Anna R. Blankstein +6 more
wiley +1 more source
Risk Factors and Clinical Severity in Chronic Venous Disease: A New Look
International Journal of Dermatology, EarlyView.Genetic factors, such as gender and positive family history, were associated with the occurrence of mild‐stage disease (CEAP C1–3). Obesity, lack of exercise, and working more than 8 h in a sitting or standing position are strongly associated with severe venous disease (CEAP C4–6).
Éva Badak +6 more
wiley +1 more source