Results 91 to 100 of about 90,290 (305)

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

VARIOUS PATTERNS OF PULMONARY VEINS OPENING IN THE LEFT ATRIUM OF HEART: A CLINICAL INSIGHT.

, 2018
Pulmonary veins carry oxygenated blood from lungs to the left atrium of heart. The four pulmonary veins open into the superior posterolateral surfaces of the left atrium, two on each side.
Rekha., Simriti
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Symptomatic paroxysmal atrial fibrillation in a patient with unilateral pulmonary vein atresia

Southwest Respiratory and Critical Care Chronicles, 2015
A 52-year-old man with symptomatic paroxysmal atrial fibrillation was offered an atrial fibrillation (AF) ablation procedure. His echocardiogram indicated that he had no structural heart disease.
Sharmila Sehli, David M Donaldson
doaj  

Development of the pulmonary vein [PDF]

International Journal of Cardiology, 2007
Moorman, Antoon F. M., Anderson, Robert H.   +1 more
openaire   +4 more sources

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source

Pulmonary intravascular blood volume changes through the cardiac cycle in healthy volunteers studied by cardiovascular magnetic resonance measurements of arterial and venous flow

Journal of Cardiovascular Magnetic Resonance, 2009
Background This study aims to present a novel method for using cardiovascular magnetic resonance (CMR) to non-invasively quantify the variation in pulmonary blood volume throughout the cardiac cycle in humans.
Arheden Hakan, Jense Erik, Ugander Martin   +2 more
doaj   +1 more source

Antenatal Betamethasone Therapy Augments Isoproterenol and Prostaglandin E2-Mediated Relaxation of Preterm Ovine Pulmonary Veins

, 1997
Antenatal glucocorticoid therapy improves pulmonary function in preterm newborns. We have determined the effect of antenatal glucocorticoid therapy on isoproterenol and prostaglandin (PG) E2-mediated relaxation in preterm ovine pulmonary veins after ...
Zhou, H., Yuansheng Gao, Jean-Francois Tolsa, Hai Shen, Gao, Y., Haiyan Zhou, Shen, H., Tolsa, J. F., Raj, J. U., J Usha Raj   +9 more
core   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Transcatheter Correction of Bilateral Partial Anomalous Pulmonary Venous Return with Intrapulmonary Dual Drainage: A Rare Entity

Life
Partial anomalous pulmonary venous return (PAPVR) with dual drainage is a very rare congenital heart anomaly. We report the case of a 6-year-old boy with PAPVR in whom both upper pulmonary veins (PVs) drain anomalously into the systemic venous ...
Dusan Andric, Andrija Pavlovic, Igor Stefanovic, Marko Pavlovic, Maja Trkulja, Maja Bijelic, Milica Kuzmanovic, Jovan Petrovic, Mirko Topalovic, Vojislav Parezanovic, Milan Djukic   +10 more
doaj   +1 more source