Results 151 to 160 of about 90,290 (305)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

A Custom Annotated Dataset for Segmentation of Pulmonary Veins, Arteries, and Airways. [PDF]

Sci Data
Liu J, Zhang Z, Niu B, Kang S, Ren J, Wang L, Xu K.   +6 more
europepmc   +1 more source

Stenosis of the left pulmonary veins after atrial fibrillation catheter ablation. [PDF]

Einstein (Sao Paulo), 2023
Estruzani T, Mitsutake LKN, Alexandre B, Ishikawa WY, Sasdelli Neto R, Szarf G, Silva MMA, Funari MBG, Paul LC, Fonseca EKUN.   +9 more
europepmc   +1 more source

Inflammation‐driven variability in drug metabolism: Insights from voriconazole treatment of HSCT recipients

British Journal of Clinical Pharmacology, EarlyView.
Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp, Martijn L. Manson, Henk‐Jan Guchelaar, Stefan Böhringer, Esther H. M. van Egmond, Peter A. von dem Borne, Jesse J. Swen   +6 more
wiley   +1 more source

Beyond the Pulmonary Veins: The Influence of Pulsed Field Ablation on the Superior Vena Cava. [PDF]

J Arrhythm
Yoshida E, Sakamoto Y, Osanai H, Asano H.   +3 more
europepmc   +1 more source

Correlation of the Flow Patterns among the Four Pulmonary Veins as Assessed by Transesophageal Echocardiography: Influence of Significant Mitral Regurgitation

, 2008
Aims: To evaluate the correlation of the flow patterns of the four pulmonary veins as assessed by transesophageal echocardiography and the influence of significant mitral regurgitation on this correlation.
黃瑞仁;林哲民;許寬立;賴凌平;林俊立;曾淵如;李源德;連文彬, HWANG, JUEY-JEN;LIN, JER-MIN;HSU, KWAN- LIH;LAI, LING-PING;LIN, JIUNN-LEE;TSENG, YUNG-ZU;LEE, YUAN-TEH;LIEN, WEN-PIN   +1 more
core  

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

British Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert, Carl M. J. Kirkpatrick, Rory Marriott, Siladitya Ray Chaudhuri, David Polidori, Bart Remmerie, Michelle P. McIntosh   +6 more
wiley   +1 more source

Catheter Ablation for Persistent Atrial Fibrillation: Rationale, Evidence, and Contemporary Strategies Beyond Pulmonary Veins. [PDF]

J Clin Med
Ruscio E, Marsilia M, Bencardino G, Narducci ML, Perna F, Comerci G, Pinnacchio G, Burzotta F, Scacciavillani R, Pelargonio G.   +9 more
europepmc   +1 more source

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source

Pulmonary Veins, Posterior Wall, and Non-Pulmonary Vein Trigger Ablation in Persistent Atrial Fibrillation and Dextrocardia. [PDF]

JACC Case Rep
Scacciavillani R, Perna F, Comerci G, Pelargonio G.   +3 more
europepmc   +1 more source