Results 41 to 50 of about 13,607 (215)

The Gravitational-wave Background Null Hypothesis: Characterizing Noise in Millisecond Pulsar Arrival Times with the Parkes Pulsar Timing Array

open access: yesThe Astrophysical Journal Letters, 2023
The noise in millisecond pulsar (MSP) timing data can include contributions from observing instruments, the interstellar medium, the solar wind, solar system ephemeris errors, and the pulsars themselves.
Daniel J. Reardon   +21 more
doaj   +1 more source

The optimal schedule for pulsar timing array observations

open access: yes, 2012
In order to maximize the sensitivity of pulsar timing arrays to a stochastic gravitational wave background, we present computational techniques to optimize observing schedules. The techniques are applicable to both single and multi-telescope experiments.
Bassa, C. G.   +6 more
core   +1 more source

Search for an Isotropic Gravitational-wave Background with the Parkes Pulsar Timing Array

open access: yesThe Astrophysical Journal Letters, 2023
Pulsar timing arrays aim to detect nanohertz-frequency gravitational waves (GWs). A background of GWs modulates pulsar arrival times and manifests as a stochastic process, common to all pulsars, with a signature spatial correlation.
Daniel J. Reardon   +28 more
doaj   +1 more source

PSR J1838−0655: X-Ray Observations with NICER and NuSTAR

open access: yesThe Astrophysical Journal
We report on the timing and spectral properties of PSR J1838-0655 using joint observations from the Neutron Star Interior Composition Explorer (NICER) and the Nuclear Spectroscopic Telescope Array (NuSTAR). By disentangling the pulsar’s emission from its
Xian-Ao Wang   +7 more
doaj   +1 more source

Pulsar Timing Response to Gravitational Waves with Spherical Wave Fronts from a Massive Compact Source in the Quadrupole Approximation

open access: yesThe Astrophysical Journal, 2023
Pulsar timing arrays (PTAs) are searching for nanohertz-frequency gravitational waves (GWs) through cross-correlation of pulse arrival times from a set of radio pulsars.
Ryousuke Kubo   +2 more
doaj   +1 more source

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang   +9 more
wiley   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

open access: yesAdvanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir   +7 more
wiley   +1 more source

Decade-long Timing of Four GMRT Discovered Millisecond Pulsars

open access: yesThe Astrophysical Journal
The discovery and timing follow up of millisecond pulsars (MSPs) are necessary not just for their usefulness in pulsar timing arrays (PTAs) but also for investigating their own intriguing properties.
Shyam S. Sharma   +3 more
doaj   +1 more source

The NANOGrav 15 yr Data Set: Detector Characterization and Noise Budget

open access: yesThe Astrophysical Journal Letters, 2023
Pulsar timing arrays (PTAs) are galactic-scale gravitational wave (GW) detectors. Each individual arm, composed of a millisecond pulsar, a radio telescope, and a kiloparsecs-long path, differs in its properties but, in aggregate, can be used to extract ...
Gabriella Agazie   +91 more
doaj   +1 more source

High signal-to-noise ratio observations and the ultimate limits of precision pulsar timing

open access: yes, 2011
We demonstrate that the sensitivity of high-precision pulsar timing experiments will be ultimately limited by the broadband intensity modulation that is intrinsic to the pulsar's stochastic radio signal. That is, as the peak flux of the pulsar approaches
Andrews   +97 more
core   +1 more source

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