Results 221 to 230 of about 43,354 (300)
The Journal of Physiology, EarlyView.Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley +1 more source
Breathing irregularities and postnatal hypoxaemia in an experimental model of essential hypertension
The Journal of Physiology, EarlyView.Abstract figure legend Neonatal spontaneously hypertensive rats (SHRs) exhibit inherent respiratory dysfunction in early life, including oscillatory breathing patterns and apnoeic events that cause oxygen desaturation and brain hypoxia, in addition to an impaired hypoxic ventilatory response.
Beatriz N. Vieira +7 more
wiley +1 more source
The Impact of Pulsatile Flow on Suspension Force for Hydrodynamically Levitated Blood Pump. [PDF]
J Healthc Eng, 2019 Fu Y, Hu Y, Huang F, Zhou M.
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Overview of cerebral small vessel disease (cSVD) pathophysiology and current modelling challenges. Left: clinical burden and key unresolved research questions. Right: neurovascular unit (NVU) architecture highlighting sites of cSVD pathology across arterioles, capillaries and venules, including interactions between endothelial ...
Sophie Beaumont +3 more
wiley +1 more source
Numerical study of pulsatile flow in composite arterial coronary grafts
, 2006 Politis, A +4 more
core +1 more source
Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies
The Journal of Physiology, EarlyView.Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu +3 more
wiley +1 more source
Pulsatile flow for improved myocardial protection
Cleveland Clinic Journal of Medicine, 1978 openaire +2 more sources
A microstructurally motivated framework to study autoregulation in the coronary circulation
The Journal of Physiology, EarlyView.Abstract figure legend A microstructurally motivated framework was constructed to simulate coronary autoregulation in symmetrically bifurcating trees at three myocardial depths: subepicardial (subepi), midwall and subendocardial (subendo). Wall mechanics of individual vessels are governed by a constrained‐mixture model, incorporating elastin, collagen ...
Matthew J. Eden +8 more
wiley +1 more source
Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 727-740, August 2026.ABSTRACT Purpose To propose a noninvasive and quantitative MRI approach to simultaneously assessing intracranial artery pulsation and paravascular cerebrospinal fluid (CSF) pulsation in the human brain. Methods We developed a 3D whole‐brain Diffusion‐prepared Cine bSSFP (DECAF) MRI technique, with improved motion‐sensitized driven‐equilibrium providing
Chang Ni +8 more
wiley +1 more source