Results 221 to 230 of about 43,390 (300)
The Journal of Physiology, EarlyView.Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley +1 more source
Breathing irregularities and postnatal hypoxaemia in an experimental model of essential hypertension
The Journal of Physiology, EarlyView.Abstract figure legend Neonatal spontaneously hypertensive rats (SHRs) exhibit inherent respiratory dysfunction in early life, including oscillatory breathing patterns and apnoeic events that cause oxygen desaturation and brain hypoxia, in addition to an impaired hypoxic ventilatory response.
Beatriz N. Vieira +7 more
wiley +1 more source
Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies
The Journal of Physiology, EarlyView.Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu +3 more
wiley +1 more source
The Impact of Pulsatile Flow on Suspension Force for Hydrodynamically Levitated Blood Pump. [PDF]
J Healthc Eng, 2019 Fu Y, Hu Y, Huang F, Zhou M.
europepmc +1 more source
Presentation of preload and afterload to isolated heart preparations
The Journal of Physiology, EarlyView.Abstract figure legend The heart can be isolated, and when this is so, it must be subjected to loading conditions. Over the past few decades, various loading methods have been developed to prescribe preload and afterload to isolated working‐heart preparations.
Esau Mhandu +4 more
wiley +1 more source
Variations in pulsatile flow around stenosed microchannel depending on viscosity. [PDF]
PLoS One, 2019 Hong H, Song JM, Yeom E.
europepmc +1 more source
Magnetic Resonance in Medicine, Volume 96, Issue 3, Page 1427-1442, September 2026.ABSTRACT Purpose To develop a robust deep learning framework for noncontrast‐enhanced functional lung MRI, overcoming the limitations of spectral decomposition in the presence of physiological nonstationarity. Methods We introduce VQ‐Wave (Ventilation/Q‐perfusion Waveform‐based Assessment of Variable Evolutions), a physics‐driven spatiotemporal ...
Grzegorz Bauman +3 more
wiley +1 more source
Ultrafast fMRI Detects Age‐Related Changes in Harmonics of Cardiac Pulsations in the Brain at 7 T
Magnetic Resonance in Medicine, Volume 96, Issue 3, Page 1206-1218, September 2026.ABSTRACT Purpose Aging impacts pulsatility of blood vessels in the brain, reflecting vascular health. Resolving characteristics of cardiac pulsatility requires faster acquisitions than traditional fMRI. An ultrafast fMRI method was developed and applied to sample several harmonics of cardiac pulsations at 7 T.
Charles Marchini +5 more
wiley +1 more source
Idiopathic Intracranial Hypertension Is Characterized by a Distinct Proteomic Profile
Annals of Neurology, Volume 100, Issue 2, Page 255-267, August 2026.Objectives The pathophysiology of idiopathic intracranial hypertension (IIH) is poorly understood and disease‐specific biomarkers are lacking. We aimed to shed light on IIH pathophysiology and identify disease‐specific biomarkers. Methods This prospective cross‐sectional cohort study included patients with new‐onset IIH and age‐, body mass index‐, and ...
Santosh D. Bhosale +17 more
wiley +1 more source