Results 61 to 70 of about 5,075,819 (283)

Study on the optimal impact stand-off distance of self-excited pulsed supercritical carbon dioxide jet based on resonance effect

Meitan xuebao
The supercritical carbon dioxide (SC-CO2) jet has a wide application prospect in drilling engineering, and its low coal breaking pressure threshold and high efficiency can improve drilling efficiency.
Yujie DENG, Yong LIU, Jianping WEI, Helian SHEN, Xiang LI, Haichao LI   +5 more
doaj   +1 more source

Genetic variation in the C-reactive protein gene and arterial stiffness: The Rotterdam Study

Artery Research, 2008
Background and aim: Arterial stiffness increases with age and has been found to predict cardiovascular disease. C-reactive protein (CRP) is an inflammation marker and has been found to be associated with arterial stiffness and risk of cardiovascular ...
M.P.S. Sie, F.U.S. Mattace-Raso, I. Kardys, M.P.M. de Maat, A.G. Uitterlinden, A. Hofman, A.P.G. Hoeks, R.S. Reneman, R. Asmar, C.M. van Duijn, J.C.M. Witteman   +10 more
doaj   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

How to detect a positive response to a fluid bolus when cardiac output is not measured?

Annals of Intensive Care, 2019
Background Volume expansion is aimed at increasing cardiac output (CO), but this variable is not always directly measured. We assessed the ability of changes in arterial pressure, pulse pressure variation (PPV) and heart rate (HR) or of a combination of ...
Zakaria Ait-Hamou, Jean-Louis Teboul, Nadia Anguel, Xavier Monnet   +3 more
doaj   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Pulse Pressure Variation Patterns in a Swine Model of Hypovolemia under Spontaneous Breathing vs. Invasive Positive-Pressure Ventilation

, 2014
OBJECTIVE: This study was performed to obtain the title of Master in Medicine, Nov/2012-Jul/2013. Improvement in cardiac output after fluid administration is known as fluid responsiveness.
Rocha,Mauricio Macário, Souza,José Marconi Almeida de, Barbosa,Adriano Henrique Pereira, Costa,Guilherme Drummond Fenelon, Carvalho,Antônio Carlos Camargo, Paola,Angelo Amato Vincenzo de   +5 more
core   +1 more source

Variations in the effect of pulse pressure on cognition based on blood pressure

The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences
Abstract Objectives This study examined the predictive utility of pulse pressure relative to blood pressure status for cognition among older adults and the potential differential effects of pulse pressure on cognition based on blood pressure status.
Mubarick Saeed, Charles F. Murchison, David S. Geldmacher, Katie M. Wheeler, Erik D. Roberson, Victor A. Del Bene   +5 more
openaire   +3 more sources

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Patient-ventilator asynchrony affects pulse pressure variation prediction of fluid responsiveness

, 2015
During partial ventilatory support, pulse pressure variation (PPV) fails to adequately predict fluid responsiveness. This prospective study aims to investigate whether patient-ventilator asynchrony affects PPV prediction of fluid responsiveness during ...
Cammarota, Giovanni, De Lucia Marta, Cammarota, Gianmaria, Antonelli Massimo, Navalesi, Paolo, Messina Antonio, De Lucia, Marta, Navalesi Paolo, Colombo, Davide, Cecconi, Maurizio, Della Corte Francesco, Colombo Davide, DELLA CORTE, Francesco, Messina, Antonio, Cammarota Gianmaria, Cecconi Maurizio, Antonelli, Massimo   +16 more
core   +1 more source