Results 231 to 240 of about 265,980 (293)

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

Advanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon, Kyungchul Noh, Minkyu Hwang, Yoon‐Jung Kim, Unjin Lee, Yeon Joo Ryu, Je‐Kyung Ryu, Sang Beom Jun, Se‐Young Choi, Woo‐Hyun Cho, Sung Joong Lee   +10 more
wiley   +1 more source

Association of estimated pulse wave velocity with asthma risk in middle-aged and older adults in China: a national cohort study. [PDF]

BMC Public Health
Cai Y, Zhang T, He Y, Xie H.
europepmc   +1 more source

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

Are Advanced Glycation End-Products and Skin Autofluorescence Associated with E-Selectin and Pulse Wave Velocity as Markers of Atherosclerosis Risk in Children with Obesity? [PDF]

Int J Mol Sci
Medyńska A, Noczyńska A, Zwolińska D.
europepmc   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Association of bioimpedance-derived parameters with pulse wave velocity: Phase angle, extracellular to intracellular water ratio, and body cell mass. [PDF]

Physiol Rep
Asano Y, Miyachi M, Nanri H, Murakami H, Gando Y, Nakagata T, Yoshida T, Okura T, Yamada Y.   +8 more
europepmc   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

A cross-sectional comparison of invasive and noninvasive aortic pulse wave velocity measurement in patients with or at risk for heart failure with preserved ejection fraction. [PDF]

Cardiovasc Diagn Ther
Asif A, Nelson MD, Shufelt C, Samuel TJ, Cook-Wiens G, Luu J, Tjoe B, Tamarappoo B, Berman DS, Bairey Merz CN, Wei J.   +10 more
europepmc   +1 more source

Saturation effect of brachial-ankle pulse wave velocity on first stroke in adults with hypertension: a prospective cohort study. [PDF]

Front Cardiovasc Med
Zhou W, Zhu L, Wang T, Yu C, Bao H, Cheng X.   +5 more
europepmc   +1 more source

Machine Learning Prediction Model for Carotid-Femoral Pulse Wave Velocity in Cardiovascular Health Assessments. [PDF]

J Clin Hypertens (Greenwich)
Xin M, Kumar V, Narisawa M, Jin C, Xu W, Cheng XW.   +5 more
europepmc   +1 more source