Results 141 to 150 of about 27,668 (261)
Coyote Range Expansion in the Human‐Modified Tropics of Mesoamerica
Coyotes have expanded their range into southeastern Mexico, Guatemala, and Belize, increasingly occupying human‐modified landscapes. This expansion is ongoing, with rising detection rates over time and records in both disturbed and forested environments, highlighting a paradox where anthropogenic change enables native carnivore expansion.
César R. Rodríguez‐Luna +17 more
wiley +1 more source
Novel antagonist APG-115 targets MDM2-p53 to induce p53-mediated apoptosis and radiosensitization in colorectal cancer. [PDF]
Yi H +5 more
europepmc +1 more source
Abstract Mesocarnivores navigate a complex risk–reward continuum in ecosystems shared with their apex counterparts, balancing scavenging opportunities with risks of mortality. However, the risks to mesocarnivores in multi‐carnivore systems are not uniform; they can vary with specific apex–meso pairings.
Wesley Binder +7 more
wiley +1 more source
Exploring the impact of hAMSCs secretome on Panc1 cells via TNF-α/NF-κB (p50/p65)/Caspase 3 signaling pathways: An <i>in vitro</i> study. [PDF]
Khalafi A, Safari F.
europepmc +1 more source
Movement decisions reflect compromised statewide connectivity for mountain lions in California
Human‐induced habitat fragmentation threatens connectivity for populations of wide‐ranging species by compromising long‐distance dispersal. We evaluated movement‐based resource selection of dispersing mountain lions (Puma concolor) to identify specific landscape conditions influencing movement decisions and connectivity between populations across the ...
Kyle D Dougherty +17 more
wiley +1 more source
Neuroprotection of IGF-1 in neonatal hypoxic-ischemic brain injury through downregulation of FoXO3a-PUMA pathway. [PDF]
Tang Y +8 more
europepmc +1 more source
Abstract TP53 mutations are found in over 50% of tumor types, including myeloproliferative neoplasms (MPNs). MPNs are characterized by a chronic phase, which may progress to secondary acute myeloid leukemia (sAML). Here, we discuss the physiological functions of p53 in hematopoiesis and its deregulation in MPNs.
Suzana da Silva‐Benedito +6 more
wiley +1 more source
Targeting CHD1L suppresses prostate cancer progression via the FOXO3-PUMA axis. [PDF]
Hui P +7 more
europepmc +1 more source
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most common non‐Hodgkin lymphoma and is an aggressive and highly heterogeneous tumor. Kaempferitrin (KPF) is a natural flavonoid glycoside that exerts a protective role in multiple human tumors. However, the impact of KPF on DLBCL remains unclear.
Han‐Shuo Zhang +3 more
wiley +1 more source

