Results 101 to 110 of about 2,535,910 (353)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The Influence of the Installation Angle of a Blade’s Low-Pressure Edge on the Cavitation Performance of Francis Pump-Turbines

Fluids
The low-pressure edge of a pump-turbine runner blade is more prone to cavitation than other parts. The installation angle of the blade’s low-pressure edge is one of the key parameters affecting the cavitation performance of the pump-turbine. Based on the
Hui Ruan, Wenxiong Chao, Xiangyang Li, Qingyang Zhang, Lvjun Qing, Chunmei Wei   +5 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Investigating the role that the Southern Ocean biological pump plays in determining global ocean oxygen concentrations and deoxygenation [PDF]

, 2013
Global ocean circulation connects marine biogeochemical cycles through the long-range transport of nutrients and oxygen with the Southern Ocean (SO) acting as a water mass crossroads. The biological pump in the SO has been shown to play an important role
Keller, David, Oschlies, Andreas
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

A robust high-efficiency cross-coupled charge pump circuit without blocking transistors [PDF]

, 2018
This document is the Accepted Manuscript version of the following article: Minglin Ma, Xinglong Cai, Yichuang Sun, and Nike George, ‘A robust high-efficiency cross-coupled charge pump circuit without blocking transistors’, Analog Integrated Circuits and ...
Cai, Xinglong, George, Nike, Ma, Minglin, Sun, Yichuang   +3 more
core   +2 more sources

To the moon: defining and detecting cryptocurrency pump-and-dumps

Crime Science, 2018
Pump-and-dump schemes are fraudulent price manipulations through the spread of misinformation and have been around in economic settings since at least the 1700s.
J. Kamps, Bennett Kleinberg
semanticscholar   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A high-efficiency and compact charge pump with charge recycling scheme and finger boost capacitor [PDF]

, 2019
A 16-phase 8-branch charge pump with finger boost capacitor is proposed to increase the power efficiency. Compared with the standard capacitor, the finger capacitor can significantly reduce the parasitic capacitance.
Bauwens, Pieter, De Pauw, Herbert, Doutreloigne, Jan, Peng, Hui   +3 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source