Results 71 to 80 of about 302,863 (304)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Numerical Analysis of Influence of Different Anti-Vortex Devices on Submerged Vortices and on Overall Performance of Vertical Mixed-Flow Pump

Fluids
The aim of this study is to compare submerged vortical structures for a pump mounted in a pump intake without any anti-vortex devices (AVDs), with a trident-like AVD or with a cone AVD. Another aim is to compare the pump characteristics (head, efficiency,
Milan Sedlář, Prokop Moravec, Vít Doubrava, Martin Komárek   +3 more
doaj   +1 more source

Injection-Seeded Terahertz Parametric Oscillator with a Ring-Cavity Configuration

Crystals, 2020
This paper reports the characteristics of an injection-seeded terahertz parametric oscillator (TPO) with a ring-cavity configuration based on the MgO:LiNbO3 crystal.
Feilong Gao, Yuan Li, Zhenhua Cong, Xingyu Zhang, Zhaojun Liu, Xiaohan Chen, Zengguang Qin, Zecheng Wang, Na Ming   +8 more
doaj   +1 more source

Hypothesized diprotomeric enzyme complex supported by stochastic modelling of palytoxin-induced Na/K pump channels [PDF]

Royal Society Open Science, 2018
The sodium–potassium pump (Na+/K+ pump) is crucial for cell physiology. Despite great advances in the understanding of this ionic pumping system, its mechanism is not completely understood. We propose the use of a statistical model checker to investigate
Gabriel D. Vilallonga, Antônio-Carlos G. de Almeida, Kelison T. Ribeiro, Sergio V. A. Campos, Antônio M. Rodrigues   +4 more
doaj   +1 more source

Light slowdown in the vicinity of cross-over resonances

, 2004
Pulse propagation is considered in an inhomogeneously broadened medium of three-level atoms in a V-configuration, dressed by a counter-propagating pump pulse.
A. Raczyński, Agarwal, Demtröder, Dutton, Fleischhauer, Fleischhauer, Harris, J. Zaremba, Kocharovskaya, Liu, M. Perdian, Matsko, Phillips, S. Zielińska-Kaniasty, Scully, Wa¸sik   +15 more
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Optical parametric generation in periodically poled KTiOPO4 via extended phase matching [PDF]

, 2007
We report an experimental demonstration of optical parametric generation in a periodically poled KTiOPO4 crystal based on the principle of mirrorless optical parametric oscillation.
Psaltis, Demetri, Pu, Ye, Tsang, Mankei, Wu, Jie   +3 more
core  

Fast-Light in a Photorefractive Crystal for Gravitational Wave Detection [PDF]

, 2008
We demonstrate superluminal light propagation using two frequency multiplexed pump beams to produce a gain doublet in a photorefractive crystal of Ce:BaTiO3. The two gain lines are obtained by two-wave mixing between a probe field and two individual pump
Hemmer, P. R., Pati, G. S., Salit, M., Shahriar, M. S., Tseng, S., Yum, H. N.   +5 more
core   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source