Results 91 to 100 of about 655,300 (307)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Occurrence Condition of Air Entrainment into a Vertical Wet-Pit Pump
Journal of Fluid Science and Technology, 2013 In the present study, we consider the air entrainment into a suction pipe which is vertically inserted down into a suction sump across a mean free-water surface.
Katsuya HIRATA +5 more
doaj +1 more source
Optical Lattice Trap for Kerr Solitons
, 2017 We show theoretically and numerically that dichromatic pumping of a nonlinear microresonator by two continuous wave coherent optical pumps creates an optical lattice trap that results in the localization of intra-cavity Kerr solitons with soliton ...
Maleki, Lute +2 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The Journal of Engineering, 2018 In order to investigate the internal flow field of an axial blood pump, two-dimensional (2D) particle image velocimetry (PIV) was applied to test the blood pump under three different conditions.
Zhiyong Xiao +4 more
doaj +1 more source
Low-thrust chemical propulsion system pump technology [PDF]
Candidate pump and driver systems for low thrust cargo orbit transfer vehicle engines which deliver large space structures to geosynchronous equatorial orbit and beyond are evaluated.
Sabiers, R. L., Siebenhaar, A.
core +1 more source
A new method of vibration analysis for the diagnosis of impeller in a centrifugal pump [PDF]
, 2014 Centrifugal pumps are widely used in many important industries such as power generation plants, chemical processes and petroleum refiners. The condition monitoring of centrifugal pumps is highly regarded by many researchers and users to minimize ...
Abdulrahman, Albraik +5 more
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source