Results 81 to 90 of about 272,665 (285)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Damages on pumps and systems: the handbook for the operation of centrifugal pumps
, 2014 Damage on Pumps and Systems. The Handbook for the Operation of Centrifugal Pumps offers a combination of the theoretical basics and practical experience for the operation of circulation pumps in the engineering industry.
Merkle, Thomas., Merkle, Thomas
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Design and analysis on the flow fluctuation of a new horizontal space multiphase crankshaft pump
The Journal of Engineering, 2018 In civil aviation ground deicing system, the traditional reciprocating pump is often used as the power supply device to ensure the physical and chemical properties of high viscosity deicing fluid.
Mengli Wu +6 more
doaj +1 more source
On the Design and Response of Domestic Ground-Source Heat Pumps in the UK [PDF]
, 2014 The design and response of ground source heat pumps coupled to vertical closed loop arrays in UK domestic applications are investigated in this article.
Underwood, Chris, Chris Underwood
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Solar Powered Borehole Pumps [PDF]
, 2008 Electricity generated by solar panels (photovoltaic power) has been used for powering pumps for many years but in the past these systems have suffered from high capital costs, low power and uncertain reliability.
core +1 more source
The Journal of Engineering, 2019 This work consists in assessing a real islanded power system from a dynamic security point of view, to support the planned installation, in the near future, of a hydro power plant with pumped storage, aiming to increase the integration of renewable ...
Maria Helena Vasconcelos +4 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source