Results 61 to 70 of about 236,334 (314)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Experimental Investigations on the Inner Flow Behavior of Centrifugal Pumps under Inlet Air-Water Two-Phase Conditions

open access: yesEnergies, 2019
Centrifugal pumps are widely used and are known to be sensitive to inlet air-water two-phase flow conditions. The pump performance degradation mainly depends on the changes in the two-phase flow behavior inside the pump.
Qiaorui Si   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Development of acoustic emission technology for condition monitoring and diagnosis of rotating machines: bearings, pumps, gearboxes, engines, and rotating structures [PDF]

open access: yes, 2006
Proof pdf available on ResearchGate (2nd May 2015 uploaded by David Mba)One of the earliest documented applications of Acoustic Emission Technology (AET) to rotating machinery monitoring was in the late 1960s.
Mba, David, Rao, Raj B. K. N.
core  

Flow Inside the Sidewall Gaps of Hydraulic Machines: A Review

open access: yesEnergies, 2020
The paper critically reviews the current state of the art in flow inside sidewall gaps of hydraulic pumps and turbines. It describes the consequences of the presence of this type of flow in turbomachinery and then relates it to other physical phenomena ...
Lucie Zemanová, Pavel Rudolf
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Practical Method for Speeding up the Cavitation Prediction in an Industrial Double-Suction Centrifugal Pump

open access: yesEnergies, 2019
Researches have over the past few years have been applying optimization algorithms to quickly find optimum parameter combinations during cavitation optimization design.
Ji Pei   +5 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Damages on pumps and systems: the handbook for the operation of centrifugal pumps

open access: yes, 2014
Damage on Pumps and Systems. The Handbook for the Operation of Centrifugal Pumps offers a combination of the theoretical basics and practical experience for the operation of circulation pumps in the engineering industry.
Merkle, Thomas., Merkle, Thomas
core  

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