Results 71 to 80 of about 271,894 (285)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Synthesis of phase-locked counter-phase modulated pumps for SBS-suppressed fiber parametric amplifiers

open access: yes, 2010
We propose and experimentally demonstrate a new all-optical technique for the generation of two optical pumps with oppositely varying carrier phases for mitigating SBS in parametric amplifiers without phase-dither transfer from pumps to ...
J. Kakande   +9 more
core   +1 more source

Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance

open access: yes
Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

From Geometric Regulation to Intelligent Design: A Review on Performance Improvement of Dual-Feedback Fluidic Oscillators

open access: yesMachines
Fluidic oscillators (FOs) are self-excited jet-generating devices without moving parts that convert steady fluid supply into oscillatory jets through inherent flow instabilities.
Ye Chu   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Performance Prediction Based on Effects of Wrapping Angle of a Side Channel Pump

open access: yesEnergies, 2019
This paper seeks to predict the performance of the side channel pump by considering the influences of different wrapping angles. Firstly, three pump cases 1, 2 and 3 are modeled with wrapping angles 15°, 30° and 45°, respectively.
Ji Pei   +6 more
doaj   +1 more source

Flow Inside the Sidewall Gaps of Hydraulic Machines: A Review

open access: yesEnergies, 2020
The paper critically reviews the current state of the art in flow inside sidewall gaps of hydraulic pumps and turbines. It describes the consequences of the presence of this type of flow in turbomachinery and then relates it to other physical phenomena ...
Lucie Zemanová, Pavel Rudolf
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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