Results 141 to 150 of about 105,404 (327)

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Small punch tensile/fracture test data for P91 material at 22 °C and a displacement rate of .0055 mm/s (second repeat test)

, 2017
Betül Gülçimen, Peter Haehner, Roger Christopher Hurst, Frits De Haan, C. C. Ramos, J. Mendes   +5 more
openalex   +1 more source

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

Advanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim, Tianxin Cao, Zhengpeng Wan, Jaesang Kim, Zhuxuan Li, Legairre A. Radden II, Rakesh Santhanam, Eunkyung Clare Ko, Tatsuya Osaki, Sarah Spitz, Hyunmin Moon, Maria Proestaki, Seokbeom Roh, Gyudo Lee, Jessie S. Jeon, Curtis R. Warren, Roger D. Kamm   +16 more
wiley   +1 more source

Improvement of the Method of Calculating Plates for Punching

Железобетонные конструкции
The article formulates proposals for improving the calculation methodology for punching. The methods in the current regulatory documents for assessing the tensile strength are based mainly on empirical dependencies obtained on the basis of numerous ...
N. N. Trekin, V. V. Krylov, K. R. Andrian   +2 more
doaj   +1 more source

Fluorescent Polymeric Nanofibers as Ratiometric Multiplexed Skin Sensors of pH and Oxygen

Advanced Healthcare Materials, EarlyView.
Fluorescent polymeric nanofibers and nanorods are produced as ratiometric sensors of two important physiological parameters: pH and oxygen. They operate by dual Forster resonance energy transfer from large number of energy donor dyes to limited number of two distinct energy acceptors, enabling simultaneous sensing of pH and oxygen.
Rémi Pelletier, Anila Hoskere Ashoka, Andrey S. Klymchenko   +2 more
wiley   +1 more source

SIMPLIFIED ANALYTICAL SOLUTION OF THE CONTACT PROBLEM ON INDENTATION OF A COATED HALF-SPACE BY A SPHERICAL PUNCH [PDF]

, 2018
Evgeniy V. Sadyrin, Andrey Vasiliev, Sergei S. Volkov, B. I. Mitrin, С. М. Айзикович   +4 more
openalex   +1 more source

A Heparin‐Functionalized Scaffold with HB‐EGF Immobilization for Tissue Engineering

Advanced Healthcare Materials, EarlyView.
In this study, a heparin‐functionalized scaffold is designed for bio‐mimicking growth factors reservoir function of extracellular matrix. Due to the presence of heparin‐binding domain, heparin‐binding epidermal growth factor‐like growth factor (HB‐EGF) is effectively and spatially captured by heparin‐functionalized scaffold.
Bowu Peng, Huajian Chen, Chengyu Lu, Tianjiao Zeng, Man Wang, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang, Guoping Chen   +8 more
wiley   +1 more source

Application of lower Punch Vibration to improve the mechanical Stability of Tablets [PDF]

, 2020
Alexander Kalies, Thomas Heinrich, Claudia S. Leopold   +2 more
openalex   +1 more source

Geometry‐Guided Osteogenesis in Bone‐on‐a‐Chip Systems Using Triply Periodic Minimal Surface Scaffolds

Advanced Healthcare Materials, EarlyView.
This study presents a bone‐on‐a‐chip platform incorporating TPMS scaffolds to study geometry‐dependent osteogenesis under dynamic flow. By tuning pore shape and solidity, it precisely controls mechanical cues, revealing how topological features and shear stress affect osteogenic differentiation and matrix formation.
Donggyu Kim, Giheon Ha, Minseok Kim, Minjin Kwak, Han‐Jun Kim, Junmin Lee   +5 more
wiley   +1 more source

Collecting wood core samples from Macassar ebony (Diospyros celebica Bakh.) for multi-purpose analysis using pickering punch

, 2022
Iskandar Zulkarnaen Siregar, Muhammad Majiidu, Fifi Gus Dwiyanti, Essy Harnelly, Ratih Damayanti, Lina Karlinasari, Mohamad Rafi, Dewi Anggraini Septaningsih, Meaghan Parker-Forney   +8 more
openalex   +1 more source