Results 31 to 40 of about 28,945 (246)
Chemistry & Biology, 2009 Schramm and coworkers have punched holes into human purine nucleoside phosphorylase by substitution of glycine for aromatic amino acid residues at a protein lid. The results of studies on the enzymes with holes illuminate hidden chemistry that occurs at the enzyme active site.
openaire +3 more sources
Advanced Functional Materials, EarlyView.The effect of a molecular‐level dual‐ionophilic chitosan passivation layer is investigated on a nanostructured paper electrode featuring an interconnected network structure of highly oxygen‐functionalized single‐walled carbon nanotubes (C‐NPE). This molecular coating enabled a high Coulombic efficiency (>99.0%) and stable cycling over 350 cycles at an ...
Jisoo Kim +11 more
wiley +1 more source
Advanced Functional Materials, EarlyView.The self‐transformed Schottky heterojunction on MXene is developed to facilitate the dissociation of Li (solvent)x+ to achieve fast Li+ desolvation to promote rapid sulfur conversion kinetics by decreasing the related barriers, contributing to high‐performance Li─S batteries under low‐temperatures.
Yongzheng Zhang +12 more
wiley +1 more source
Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection
Advanced Functional Materials, EarlyView.Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung +6 more
wiley +1 more source
Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid
Advanced Functional Materials, EarlyView.In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang +16 more
wiley +1 more source
Advanced Functional Materials, EarlyView.This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao +9 more
wiley +1 more source
Advanced Functional Materials, EarlyView.An entropy‐tuned niobium‐based oxide (ETNO) anode for fast‐charging lithium‐ion batteries are presented, engineered via multi‐cation doping. The synergistic effects of entropy tuning result in excellent rate capability and long‐term durability under ultrafast charging conditions.
Yoojin Ahn +6 more
wiley +1 more source
Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions
Advanced Functional Materials, EarlyView.An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park +10 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Particular thermal metamaterials are widely used as daytime radiative coolers merely by embedding thermally emissive nanoparticles (NPs) in liquid resins to form scalable, yet highly efficient cooling films in a cost‐effective way. However, randomly dispersed NPs, prevalently used thus far, cause strong scattering, limiting NP content and cooling ...
YongDeok Cho +10 more
wiley +1 more source