Results 61 to 70 of about 1,682 (240)

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

Advanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner, Raith Nowak, Stephanie M. Kronstadt, Nicholas H. Pirolli, Talia J. Solomon, Kristin Nikolov, William Pieper Holeman, Ian M. Smith, Kimberly M. Stroka, John P. Fisher, Steven M. Jay   +10 more
wiley   +1 more source

Punching shear in concrete reinforced flat slabs with steel fibers and shear reinforcement

Revista IBRACON de Estruturas e Materiais, 2018
Steel fibers in reinforced concrete increase the performance of slab-column connection once they increase ductility and energy absorption capacity of the concrete. The use of fibers in flat slabs may increase strength and change the mode of failure.
T. H. MUSSE, E. A. P. LIBERATI, L. M. TRAUTWEIN, R. B. GOMES, G. N. GUIMARÃES   +4 more
doaj   +1 more source

Microfluidic Hydroporation Platform for Effective Allogeneic CAR‐T Cell Production and Subsequent Functional Cytotoxicity Analysis

Advanced Materials Technologies, EarlyView.
The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon, Sein Kim, Hyun‐Young Kim, Duck Cho, Sungsu Park, Seohyun Kim, Aram J. Chung   +6 more
wiley   +1 more source

Experimental Study on Punching Shear Behavior of Ultra-High-Performance Concrete (UHPC) Slabs

Buildings
This study assesses the punching shear characteristics of ultra-high-performance concrete (UHPC) slabs in two phases. The initial phase involved experimental tests to determine the critical thickness differentiating punching shear failure and flexural ...
Junping Liu, Baochun Chen, Hamdy M. Afefy, Khaled Sennah   +3 more
doaj   +1 more source

Punching shear resistance of reinforced concrete footings: evaluation of design codes

Revista IBRACON de Estruturas e Materiais, 2018
Punching is a possible failure mode for slender footings and it may lead a structure to ruin through progressive collapse. Although footing present different geometric characteristics, their punching shear design is based on the empirical methods used ...
D. F. A. SANTOS, A. F. LIMA NETO, M. P. FERREIRA   +2 more
doaj   +2 more sources

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

Advanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto, Manuel Alejandro Vazquez Valle, Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Iván Velasco, Genaro Vázquez‐Victorio, Itzel Escobedo‐Avila   +6 more
wiley   +1 more source

Punching strengthen

Alexandria Engineering Journal, 2015
An experimental and analytical study on the punching strengthening of reinforced concrete two-way slabs using external steel plates is presented. Five reinforced concrete square slabs of 100 mm thickness were tested over simply supported four sides of ...
Hazem M.F. Elbakry, Said M. Allam
doaj   +1 more source

Additive Manufacturing of Patient‐Specific Intracranial Aneurysm Cell Culture Models

Advanced Materials Technologies, EarlyView.
Patient‐specific intracranial aneurysm models were fabricated using chocolate moulding, 3D printed water‐soluble cores, and direct resin 3D printing. Moulding PDMS around sacrificial cores made of chocolate or 3D printed water‐soluble resin yielded accurate, expandable, and endothelializable models that outperformed resin‐based approaches.
Chloe M. de Nys, Jaimee‐Lee Wood, James I. Novak, Danilo Carluccio, Craig D. Winter, Ashley R. Murphy, Mark C. Allenby   +6 more
wiley   +1 more source

Magnetic Textiles: A Review of Materials, Fabrication, Properties, and Applications

Advanced Materials Technologies, EarlyView.
Magnetic textiles (M‐textiles) are emerging as a programmable materials platform that merges magnetic matter with hierarchical textile structures. This article consolidates magnetic material classes, textile architectures, and fabrication and magnetization strategies, revealing structure–property–function relationships that govern magneto‐mechanical ...
Li Ke, Moses Kumi, Xiaoming Tao, Junhong Pu   +3 more
wiley   +1 more source

Bamboo Medical Application: A State‐of‐the‐Art Review

Advanced Materials Technologies, EarlyView.
This review presents a structured classification of bamboo's current use in healthcare. It organizes applications into medical textiles and medical devices, with further divisions based on function and level of invasiveness. It also examines material utilization based on bamboo's structural role, highlighting how it supports both protective and ...
Haymanot Beza Lamesgin, Koosje van der Stoel, Vera Popovich, Paul Breedveld   +3 more
wiley   +1 more source