Results 151 to 160 of about 331,920 (301)

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Subserosal Indocyanine Green Mapping in Colorectal Surgery Using an Adjustable Laparoscopic Injection Needle. [PDF]

J Anus Rectum Colon
Nagata J, Sannomiya H, Nitta K, Koga A, Akiyama Y, Yamauchi M, Mori Y, Sato N, Tamura T, Shibao K, Hirata K.   +10 more
europepmc   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Real-time Thermographic Vein Visualization and Extravasation Monitoring During Radiopharmaceutical Injection for Bone Scintigraphy. [PDF]

In Vivo
Kageyama M, Konishi K, Ikenohira T, Wakabayashi K, Yamashita R, Tanahashi Y, Ozaki K, Goshima S, Nakamura K.   +8 more
europepmc   +1 more source

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Safety and complications of upper pole puncture in supine percutaneous nephrolithotomy. [PDF]

World J Urol
Villanueva-Congote J, Li YW, Segall M, Gokce M, Proietti S, Giusti G, Garcia JET, Manzo B, Yaghoubian A, Gonzalez M, Ajayi L, Wollin DA, Eisner BH.   +12 more
europepmc   +1 more source

Postdural Puncture Headache (PDPH)

, 2016
Postdural puncture headache (PDPH) is probably the most common complication following neuraxial anesthesia or analgesia in the obstetric patient. Intentional puncture of the dura (by way of a spinal needle) or inadvertent dural puncture (by epidural ...
Devroe, Sarah, Van De Velde, Marc, Roofthooft, Eva   +2 more
core  

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Applied Design of Corrugated Board Properties to Mitigate Puncturing in Parcel Handling Distribution Chains

BioResources
Corrugated board boxes are used for the majority of parcel shipments. These boxes, particularly in e-commerce shipments, often suffer damages such as crushing and puncturing.
Martin Holmvall, Mats Holmgren
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