Results 51 to 60 of about 448,670 (246)

Filling the holes: Evolving excised binary black hole initial data with puncture techniques

open access: yes, 2007
We follow the inspiral and merger of equal-mass black holes (BHs) by the moving puncture technique and demonstrate that both the exterior solution and the asymptotic gravitational waveforms are unchanged when the initial interior solution is replaced by ...
Baumgarte, Thomas W.   +4 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

The statistics of the trajectory in a certain billiard in a flat two-torus

open access: yes, 2003
We consider a billiard in the punctured torus obtained by removing a small disk from the two-dimensional flat torus, with trajectory starting from the center of the puncture. In this case the phase space is given by the range of the velocity only.
Boca, Florin P.   +2 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Design and application of a medical handheld infrared veins finder (一种医用静脉血管显像装置的设计与应用)

open access: yes中西医结合护理
The veins finder helps the operator clearly display the position, thickness and direction of the blood vessel, so as to improve the puncture efficiency.
XU Hao (徐浩)   +2 more
doaj   +1 more source

Puncture black hole initial data in the conformal thin-sandwich formalism

open access: yes, 2011
We revisit the construction of puncture black hole initial data in the conformal thin-sandwich decomposition of Einstein's constraint equations. It has been shown previously that this approach cannot yield quasiequilibrium wormhole data, which connect ...
Baumgarte, Thomas W.
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Application of improved 3D digital guide plate-assisted guided puncture in microballoon compression for primary trigeminal neuralgia

open access: yes口腔疾病防治, 2023
Objective To investigate the clinical efficacy and application value of an improved 3D-printed guide plate for the treatment of primary trigeminal neuralgia (PTN) by percutaneous microballoon compression (PMC).
YANG Yinghui   +6 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

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