An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu +10 more
wiley +1 more source
<i>Glaphyrus festivus</i> Ménétriés, 1836 and related species in Turkey and Armenia (Coleoptera, Glaphyridae). [PDF]
Ghrejyan T +3 more
europepmc +1 more source
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo +6 more
wiley +1 more source
Four new species of the genus <i>Lyroda Say</i> (Hymenoptera, Crabronidae) from China, with a key to Chinese species. [PDF]
Li C, Li Q, Ma L.
europepmc +1 more source
A versatile framework integrates addressable electrothermal actuation and strain‐constraint mechanisms to construct programmable shape‐morphing soft matter systems. By combining an analytical inverse design strategy for high‐fidelity 3D surface reconstruction with deep learning‐based closed‐loop control, this approach enables zero‐energy shape locking,
Kai Liu +5 more
wiley +1 more source
Two new <i>Margarinotus</i> Marseul, 1853 from Jiangxi, Guangxi, and Guangdong provinces (China), with an updated key to all Chinese species (Coleoptera, Histeridae, Histerinae, Histerini). [PDF]
Zheng J, Yang H, Lackner T.
europepmc +1 more source
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu +10 more
wiley +1 more source
<i>Scuticeratina</i>: A new subgenus of small carpenter bees (Hymenoptera, Apidae, Xylocopinae) from Indomalaya. [PDF]
Sless TJL, Tucker EM, Rehan SM.
europepmc +1 more source
THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong +16 more
wiley +1 more source
Type material of South American <i>Pimpla</i> Fabricius, 1804 (Hymenoptera, Ichneumonidae) housed in the Instituto Fundación Miguel Lillo, Argentina. [PDF]
Pádua DG, Pérez EC, Araujo RO.
europepmc +1 more source

