Results 91 to 100 of about 1,356 (249)
Advanced Intelligent Discovery, EarlyView.A machine learning‐guided self‐driving laboratory screened over 500 nickel‐based layered double‐hydroxide catalysts for alkaline oxygen evolution. Out of the eight metals, the robot uncovered a quaternary Ni–Fe–Cr–Co catalysts requiring only 231 mV overpotential to reach 20 mA cm−2.
Nis Fisker‐Bødker +3 more
wiley +1 more source
Advanced Intelligent Systems, EarlyView.We present a novel AI‐integrated implantation‐on‐chip platform that enables mimicking and monitoring the maternal–fetal interactions at the early phases of human embryo implantation with high spatiotemporal resolution. The complexity of the trophoblast invasion process was addressed by conducting the analysis at global (rate of invasion) and local ...
Joanna Filippi +12 more
wiley +1 more source
Angewandte Chemie, EarlyView.Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee +5 more
wiley +2 more sources
Dias de insurreição em busca do sublime: as cenas punk portuguesas e brasileiras
Sociedade e EstadoResumo Este artigo centra-se na explicação e compreensão das representações acerca da autenticidade estética, artística e vivencial por parte de atores das cenas punk portuguesas e brasileiras num arco temporal que se situa entre 1977 e 2016.
Paula Guerra, Pedro Martins de Menezes
doaj +1 more source
Dielectric Elastomer Actuators as Safe and Effective Tools for Mechanostimulation of Human Cells
Advanced Intelligent Systems, EarlyView.Replicating physiological forces is crucial for realistic cell models. Dielectric elastomer actuators (DEAs) offer a soft alternative, though their high voltages raised toxicity concerns. We demonstrate that DEA stimulation causes no cell damage, cell death or cell‐cycle disruption, while activating mechanosensitive responses.
Simon Holzer +6 more
wiley +1 more source
Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization
Angewandte Chemie, EarlyView.The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu +6 more
wiley +2 more sources
Adaptive Collision Sensitivity for Efficient and Safe Human–Robot Collaboration
Advanced Intelligent Systems, EarlyView.An adaptive collision‐sensitivity framework uses each robot link's effective mass to estimate contact forces online and decide when collaborative robots should stop or continue. Tested on simulated and real UR10e and simulated KUKA arms, it maintains conservative force estimates while reducing unnecessary stops and increasing task productivity. What is
Lukas Rustler +2 more
wiley +1 more source
Angewandte Chemie, EarlyView.Reducing a nitro‐derivatized arylimido‐polyoxometalate (POM) reversibly switches on its second‐order NLO response, contrasting with prior donor‐functionalized systems that switch off upon reduction. Attenuation of charge‐transfer (CT) to the POM upon reduction gives a more strongly dipolar imido/π‐bridge to ─NO2 CT, signal enhancement of up to 15× (β ...
Claire F. Jones +7 more
wiley +2 more sources
Australian Journal of Social Issues, EarlyView.ABSTRACT This study explored the mediating influences of access to social activities, social services, and health and medical services on the relationship between social determinants of health and health‐related quality of life. A survey of 602 adults was conducted in a regional area of Australia.
Candice Oster +4 more
wiley +1 more source