Results 141 to 150 of about 15,986,900 (239)

Extracting a Robust U.S. Business Cycle Using a Time-Varying Multivariate Model-Based Bandpass Filter [PDF]

In this paper we investigate whether the dynamic properties of the U.S. business cycle have changed in the last fifty years. For this purpose we develop a flexible business cycle indicator that is constructed from a moderate set of macroeconomic time ...
Drew Creal, Siem Jan Koopman, Eric Zivot
core  

Exposure to Predators Induces Phenotypic Plasticity in Cone Opsin Expression Profiles but not in Eye Size of Female Trinidad Guppies. [PDF]

Zool Stud
Chang CH.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

A comparison of the real-time performance of business cycle dating methods [PDF]

This paper evaluates the ability of formal rules to establish U.S. business cycle turning point dates in real time. We consider two approaches, a nonparametric algorithm and a parametric Markov-switching dynamic-factor model.
Marcelle Chauvet, Jeremy M. Piger
core  

Eye-Tracking Assessment of Visual, Oculomotor, and Pupillary Biomarkers During Reading in Parkinson's Disease. [PDF]

Life (Basel)
Cabrera-Guardiola I, Herrero-Gracia A, El-Asmak-El-Harrak A, Arcas-Carbonell M, Sanchez-Cano A, Díez-Ajenjo MA, Orduna-Hospital E.   +6 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Impact of Human Melanopsin Gene (OPN4) Polymorphisms (I394T, P10L) on Nocturnal Melatonin and Daily Rhythms in Young Adults. [PDF]

J Pineal Res
Vicente-Martínez J, Bonmatí-Carrión MÁ, López-Parra AM, Madrid JA, Almaida-Pagán PF, Rol MA.   +5 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Tadpole Pupil

Infrared video recording of the patient shown in the previous slide showing a magnified view of the transient pulling on the dilator muscle, causing an irregular pupil.
Randy Kardon, MD, PhD
core  

Vagal nerve stimulation induces vascular oscillations and enhances long-term learning. [PDF]

iScience
Chen JU, Ikoma Y, Matsui K.
europepmc   +1 more source