KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Sex and age modulate the relationship between melanopsin-dependent light sensitivity and chronotype. [PDF]
van der Zwet G +10 more
europepmc +1 more source
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
The Contribution of the Locus Ceruleus-Norepinephrine System to the Coupling between Pupil-Linked Arousal and Cortical State. [PDF]
Weiss E, Liu Y, Wang Q.
europepmc +1 more source
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Pupillometry for pain assessment in noncommunicating children in the pediatric intensive care unit: a prospective accuracy study. [PDF]
Portefaix A +7 more
europepmc +1 more source
Two Cases of Fibrin Membrane-Induced Pupillary Block Treated With Neodymium-Doped Yttrium Aluminium Garnet (Nd:YAG) Laser After Cataract Surgery in Dogs. [PDF]
Yoon H +6 more
europepmc +1 more source
Retrospective evaluation of the prevalence of known and presumed hereditary eye diseases in a population of Labradoodles referred for ophthalmic screening examinations in the Netherlands. [PDF]
Goossens LT +3 more
europepmc +1 more source
Locus coeruleus modulation of neurophysiological sensory selectivity differs in autism and other mental health conditions. [PDF]
Müller AK +3 more
europepmc +1 more source

