Results 31 to 40 of about 5,493 (223)

The pupillary light reflex (PLR) as a marker for the ability to work or drive – a feasibility study

Journal of Occupational Medicine and Toxicology, 2021
Background The PLR (pupillary light reflex) can be a marker for pathological medical conditions, such as neurodegenerative or mental health disorders and diseases as well as marker for physiological alterations, such as age, sex or iris color.
Andrea Kaifie, Martin Reugels, Thomas Kraus, Michael Kursawe   +3 more
doaj   +1 more source

Atypical Pupil Reactions in Brain Dead Patients

Brain Sciences, 2021
Background: During routine diagnosis of brain death, changes in pupil diameter in response to the stimulation of peripheral nerves are sometimes observed.
Joanna Sołek-Pastuszka, Małgorzata Zegan-Barańska, Jowita Biernawska, Marcin Sawicki, Waldemar Iwańczuk, Kornel Chełstowski, Romuald Bohatyrewicz, Wojciech Dąbrowski, Klaudyna Kojder   +8 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

Advanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du, Yinming Li, Ziyue Li, Yuedan Wang, Shaopeng Li, Yijie Wang, Yingying Qu, Bingyang Lv, Ying Li, Ting Chen, Yu Zhou, Xuan Xiao   +11 more
wiley   +1 more source

Effect of Pharmacological Mydriasis on the Intraocular Pressure in Eyes with Filtering Blebs Compared to Normal Eyes: A Pilot Study

Clinical Ophthalmology, 2022
Hani M Gharieb Ibrahim Ophthalmology Department, Ain Shams University, Cairo, EgyptCorrespondence: Hani M Gharieb IbrahimOphthalmology Department, Ain Shams University Faculty of Medicine, Ramsees Street, Abbaseya, Cairo, Egypt, Email hani.gharieb@med ...
Ibrahim HMG
doaj  

Comparative analysis of endothelial cell loss following phacoemulsification in pupils of different sizes

Indian Journal of Ophthalmology, 2017
Purpose: To compare Endothelial cell(EC) loss following Phacoemulsification (PKE) in pupils of different sizes. Methods: A prospective double masked observational study in which a total of 150 eyes of 150 patients between 50 & 70 years of age with senile
Rakesh Maggon, Raghudev Bhattacharjee, Sandeep Shankar, Rajesh Chandra Kar, Vivek Sharma, Shyamal Roy   +5 more
doaj   +1 more source

Eye‐Brain Neuroimmune Axis Enables Long‐Term Survival in Glioblastoma by Modulating Brain Immune Surveillance and Neuronal Excitability

Advanced Science, EarlyView.
The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui, Lulu Qian, Binbin Chu, Xuan Qin, Menglin Wu, Minke Wu, Tongyu He, Baochuan Zhang, Bin Song, Yao He   +9 more
wiley   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

Design of Photocatalytic Composite Coatings for Formaldehyde Removal Based on the Visual Effects of Wood Furniture

Advanced Science, EarlyView.
This work develops photocatalytic coatings for indoor formaldehyde removal on wood surfaces. It explores coating‐induced color variations and visual perception via eye‐tracking tests. Combined with XGBoost and Bayesian optimization, an intelligent design framework is established to guide the optimization of visually friendly wood photocatalytic ...
Xinyue Wei, Shuyuan Chen, Xinlong Zhou, Han Wang, Wei Guo, Xiaoting Niu, Wei Li, Zhen Ding, Haiyuan Chi   +8 more
wiley   +1 more source

OPHTHALMOSCOPY- A USEFUL BUT NEGLECTED SKILL BY THE NON- OPHTHALMOLOGISTS DOCTORS

Pakistan Armed Forces Medical Journal, 2010
Objectives: Ophthalmoscopy is considered an integral part of physical examination of patients in many disciplines of medicine. A number of life threatening conditions may be revealed by ophthalmoscopy and hence can be dealt in time.
Dr Ibrar Hussain, Danish Zafar, Sadia Sethi, Muhammad Arif   +3 more
doaj   +2 more sources