Pupillometric analysis for assessment of gene therapy in Leber Congenital Amaurosis patients [PDF]
Background: Objective techniques to assess the amelioration of vision in patients with impaired visual function are needed to standardize efficacy assessment in gene therapy trials for ocular diseases.
Bennett, Jean, M.D. +5 more
core +3 more sources
Comparison of the qCON and qNOX indices for the assessment of unconsciousness level and noxious stimulation response during surgery [PDF]
The objective of this work is to compare the performances of two electroencephalogram based indices for detecting loss of consciousness and loss of response to nociceptive stimulation.
Agustí, Mercé +8 more
core +2 more sources
Pupillary responses to single and sinusoidal light stimuli in diabetic patients
We examined effects of diabetes mellitus (DM) on the pupillary light reflex (PLR). Phasic pupillary response to a single light stimulus (200 ms) (pPLR) and to continuous sinusoidal stimuli with four different frequencies (0.1, 0.3, 0.7, 1.3Hz) (cPLR ...
Wolfgang H. Zangemeister +2 more
doaj +1 more source
RdgB2 is required for dim-light input into intrinsically photosensitive retinal ganglion cells. [PDF]
A subset of retinal ganglion cells is intrinsically photosensitive (ipRGCs) and contributes directly to the pupillary light reflex and circadian photoentrainment under bright-light conditions.
Berson, David M +8 more
core +2 more sources
Comparing two captive bolt devices on market age Pekin ducks
Summary: The objective of this study was to determine the efficacy of 2 captive bolt devices in the euthanasia of market age Pekin ducks. One hundred twenty ducks were euthanized using either a commercially available captive bolt device (Zephyr-EXL, n ...
A.M. Stiewert, G.S. Archer
doaj +1 more source
Regulatory effects of blood constituents on the function and metabolism of the cat brain in perfusion ezperiments. Brain perfusion with artificial blood containing low molecular dextran and amino acids [PDF]
As a link in a series of studies on the effects of blood constituents on the brain function by means of brain perfusion, we used four kinds of artificial blood; namely, the blood containing a low molecular dextran, one containing glutamic acid, one ...
Edamatsu, Kazuyasu +5 more
core +1 more source
The pupillary light response reveals the focus of covert visual attention. [PDF]
The pupillary light response is often assumed to be a reflex that is not susceptible to cognitive influences. In line with recent converging evidence, we show that this reflexive view is incomplete, and that the pupillary light response is modulated by ...
Sebastiaan Mathôt +3 more
doaj +1 more source
Monitoring Cognitive and Emotional Processes Through Pupil and Cardiac Response During Dynamic Versus Logical Task [PDF]
The paper deals with the links between physiological measurements and cognitive and emotional functioning. As long as the operator is a key agent in charge of complex systems, the definition of metrics able to predict his performance is a great challenge.
A Bechara +40 more
core +3 more sources
Investigation of light-induced lacrimation and pupillary responses in episodic migraine.
The purpose of this pilot study was to investigate the light-induced pupillary and lacrimation responses mediated by intrinsically photosensitive retinal ganglion cells (ipRGCs) in migraine.
Marija Zivcevska +5 more
doaj +1 more source
Background: Physicians currently measure the pupil diameter and the pupillary light reflex with visual observations using a ruler and a traditional penlight, leading to possibly inaccurate and subjective assessments.
Joji Kotani +7 more
doaj +1 more source

