Results 171 to 180 of about 799,066 (314)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Abnormal pupils at the bedside: rapid recognition of neurologic and systemic emergencies in acute care settings. [PDF]

Int J Emerg Med
Penney DC, Rushetsky ZM, Penney DW.
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Policy on the move: active travel to school among 7-16-year-olds in Wales and its links to school policy and socio-demographic factors. [PDF]

BMC Public Health
Morgan K, Liu S, Ouerghi S, Kolovou V, Bradley J, Pilkington P.   +5 more
europepmc   +1 more source

Educational Effects of Alternative Secondary School Tracking Regimes in Germany [PDF]

This paper examines educational outcomes of pupils selected to secondary school types by different tracking regimes in a German state: The traditional regime of streaming pupils after fourth grade of elementary school is compared to a regime in which ...
Weber, Andrea
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Intervention for minimizing the risk of drop-out in music school pupils-an exploratory study. [PDF]

Front Psychol
Kavčič Pucihar A, Zadnik K, Zamrnik B, Plamberger P.   +3 more
europepmc   +1 more source

Assessing pupils' abilities [PDF]

Stephen Gibbons and Arnaud Chevalier investigate differences between pupils' test scores and their teachers' assessments.
Arnaud Chevalier, Steve Gibbons
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gendered perspectives of yoga in the Key Stage 1 classroom: Qualitative content analysis indicates contrasting views of teachers and pupils. [PDF]

PLoS One
Wilkin K, Thornton C, Allen-Baker G.
europepmc   +1 more source