Results 101 to 110 of about 6,236 (222)

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

MicroRNA‐130a‐3p Targets the Androgen‐Related Transcription Factor MAFB: Effects on Proliferation, Migration, Apoptosis, and Cell Cycle in Hypospadias

Pediatric Discovery, EarlyView.
MicroRNA‐130a‐3p targets and inhibits MAFB expression, leading to the development of hypospadimas. MicroRNA‐130a‐3p inhibits the expression of MAFB, disrupts the normal processes of cell proliferation, migration, cell apoptosis, and cycle progression, and ultimately leads to the development of hypospadias.
Jiaxin Zhou, Yixuan Wang, Zhicheng Zhang, Qiang Zhang, Zhenmin Liu, Hongsong Chen, Xingguo Luo, Chunlan Long, Lianju Shen, Xing Liu, Guanghui Wei   +10 more
wiley   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell‐Derived Microvesicles Alleviate Bronchopulmonary Dysplasia in Preterm Rats by Inhibiting Neutrophil Extracellular Trap Formation

Pediatric Discovery, EarlyView.
Excessive neutrophil extracellular trap (NET) extrusion (NETosis) links prenatal inflammation to bronchopulmonary dysplasia (BPD) pathogenesis. Treatment with human umbilical cord mesenchymal stem cell‐derived microvesicles suppresses NET formation, reduces lung injury, and promotes alveolarization in a preterm rat model, offering a promising cell‐free
Yi Lu, Wen Tan, Xiao Yang, Tingting Luo, Chenghao Mei, Huaqin Bu, Jinhua Ma, Chao Gong, Li Zhong, Ou Zhou, Daiyin Tian   +10 more
wiley   +1 more source

Effects of bioinsecticide exposure route on aphids and their natural enemies in oilseed rape

Pest Management Science, EarlyView.
Fatty acids, silicone polymers and surfactants reduced aphid numbers but caused natural enemy mortality under direct exposure, while minimal residual activity suggests potential for targeted, compatible use in integrated pest management. Abstract BACKGROUND Myzus persicae Sulzer and Brevicoryne brassicae L.
Aimee J. Tonks, Tom W. Pope, Simon Cooper, Joe M. Roberts   +3 more
wiley   +1 more source

Effects of pupal hypoxia duration and holding temperature on quality control parameters of sterile Queensland fruit fly

Pest Management Science, EarlyView.
Queensland fruit fly pupae tolerate hypoxia up to 2 days without compromising quality. Prolonged hypoxia, especially at 25 °C, reduces emergence and flight ability. Storage at 18 °C is recommended. Abstract BACKGROUND The sterile insect technique is used to eradicate outbreaks of Queensland fruit fly (Q‐fly) Bactrocera tryoni (Froggatt) in fruit‐fly ...
Sushil K. Gaire, Saluna Pokhrel, Polychronis Rempoulakis, Phillip W. Taylor, Bishwo P. Mainali   +4 more
wiley   +1 more source

Puppy parties and beyond: the role of early age socialization practices on adult dog behavior

Veterinary Medicine: Research and Reports, 2015
Tiffani J Howell, Tammie King, Pauleen C Bennett School of Psychology and Public Health, La Trobe University, Bendigo, VIC, Australia Abstract: The most common role of a domestic dog in the developed world currently is that of companion.
Howell TJ, King T, Bennett PC
doaj  

Mapping the global threat of Mythimna separata (Walker) and its economic implications for Brazil's agriculture

Pest Management Science, EarlyView.
Global models identified high‐risk areas for Mythimna separata invasion, highlighting major economic vulnerability for Brazilian crops and guiding targeted prevention and management strategies. Abstract BACKGROUND Identifying high‐risk areas for the introduction of invasive alien species is particularly important for agricultural pests with a broad ...
Gabriel Dorotel da Silva Ferreira, Cesar Augusto Marchioro   +1 more
wiley   +1 more source

Dose‐dependent efficacy of a novel dsRNA‐based solution containing vadescana for Varroa destructor control

Pest Management Science, EarlyView.
Vadescana is a novel dsRNA‐based product that targets Varroa fecundity. Vadescana applied at 4 g/brood box in one application was most effective at reducing Varroa populations for up to 18 weeks. Abstract BACKGROUND A novel dsRNA‐based product, containing a molecule called vadescana, interferes with Varroa destructor (Anderson and Trueman) fecundity ...
Briana E Price, Ryan Kuesel, Taylor Reams, Brian Manley, James Masucci, Brandon K Hopkins   +5 more
wiley   +1 more source

Transcriptomic resources and functional validation of RNAi in the cabbage seedpod weevil, Ceutorhynchus obstrictus

Pest Management Science, EarlyView.
Transcriptome sequencing of Ceutorhynchus obstrictus revealed RNA interference (RNAi) targets; double‐stranded RNA microinjection reduced transcript levels and increased mortality, with αCOP and Rop showing strongest lethal effects, indicating promising RNAi‐based pest control candidates.
Apurva Vikas Sabnis, Triin Kallavus, Éricmar Avila Dos Santos, Liina Soonvald, Riina Kaasik, Silva Vilumets, Clauvis Nji Tizi Taning, Kristof De Schutter, Eve Veromann   +8 more
wiley   +1 more source

Parvoviral hemorrhagic gastroenteritis and its therapeutic intervention in a case of 5-month-old puppy. [PDF]

Companion Anim Health Genet
Habte D, Wondimagegnehu K, Fhetanegest D.   +2 more
europepmc   +1 more source