PuraStat RADA16 Self-Assembling Peptide Reduces Postoperative Abdominal Adhesion Formation in a Rabbit Cecal Sidewall Injury Model [PDF]
Objective: To evaluate the effect of PuraStat (2.5% RADA16) administration on postoperative abdominal adhesion formation in an in vivo model.Methods: Anesthetized New Zealand white rabbits underwent cecal sidewall abrasion surgery in which the cecal ...
Eun Seok Gil, Elton Aleksi, Lisa Spirio
doaj +5 more sources
Impact of Using Self-Assembling Peptide (PuraStat) on Anastomotic Ulcers-A Multicenter Case Series. [PDF]
Treatment of anastomotic ulcers, also known as marginal ulcers, is challenging, especially when established techniques have failed. PuraStat is a biocompatible synthetic peptide gel that is indicated for hemostasis of bleeding in the gastrointestinal ...
Oza VM +9 more
europepmc +5 more sources
Cystoscopic application of PuraStat<sup>®</sup> in the treatment of radiation-induced haemorrhagic cystitis. [PDF]
The use of radiotherapy has increased in recent years, especially for pelvic neoplasms, and this can result in long-term complications such as recurrent haemorrhagic radiation cystitis (RHC).
Darwazeh H +3 more
europepmc +5 more sources
Response to comment on "PuraStat for gastrointestinal bleeding management: Effective approach for endoscopic prevention and rescue therapy" [PDF]
Roberta Maselli +3 more
doaj +5 more sources
PuraStat in gastrointestinal bleeding: results of a prospective multicentre observational pilot study [PDF]
Abstract Background A recently developed haemostatic peptide gel for endoscopic application has been introduced to improve the management of gastrointestinal bleeding. The aim of this pilot study was to evaluate the feasibility, safety, efficacy and indication profiles of PuraStat in a clinical setting.
Federica Branchi +28 more
core +10 more sources
Rapidly Progressive Coexistence of Gastric Antral Vascular Ectasia (GAVE) and Portal Hypertensive Gastropathy (PHG) Presenting With Iron Deficiency Anaemia: Successful Use of PuraStat in a Patient With Implantable Cardioverter-Defibrillator (ICD). [PDF]
Gastric antral vascular ectasia (GAVE), or "watermelon stomach", is an uncommon but important cause of chronic gastrointestinal blood loss and iron deficiency anaemia (IDA).
Alafifi M, Shata M, Heiba K, Emara A.
europepmc +4 more sources
Clip Closure and PuraStat for Prevention of Clinically Significant Delayed Bleeding after Colorectal Endoscopic Submucosal Dissection: A Prospective, Observational Study [PDF]
Background and aims. Clinically significant delayed bleeding (CSDB) may complicate endoscopic colorectal submucosal dissection (ESD). We aimed to assess the efficacy of preventive measures for CSDB. Methods.
Mihai Ciocîrlan +8 more
doaj +5 more sources
Gastric antral vascular ectasia (GAVE) is a gastric hemorrhagic disease associated with chronic liver disease. Argon plasma coagulation is widely used to control gastrointestinal bleeding due to GAVE.
Yoshitsugu Misumi +4 more
doaj +3 more sources
Efficacy of
ELECTROSURGICAL COAGULATION IS widely used for hemostasis during colorectal endoscopic submucosal dissection (ESD). However, its excessive application can cause thermal injury to deeper layers, leading to peritonitis or post-ESD coagulation syndrome ...
Taishi Okumura +2 more
semanticscholar +4 more sources
Emergency Endoscopic Hemostasis for Gastrointestinal Bleeding Using a Self-Assembling Peptide: A Case Series [PDF]
Background and Objectives: A novel synthetic self-assembling peptide, PuraStat, has been introduced as a hemostatic agent. This case series aimed to evaluate the clinical efficacy of PuraStat for gastrointestinal bleeding during emergency endoscopy ...
Takashi Murakami +7 more
doaj +3 more sources

