Results 11 to 20 of about 358 (116)

PuraStat RADA16 Self-Assembling Peptide Reduces Postoperative Abdominal Adhesion Formation in a Rabbit Cecal Sidewall Injury Model [PDF]

Frontiers in Bioengineering and Biotechnology, 2021
Objective: To evaluate the effect of PuraStat (2.5% RADA16) administration on postoperative abdominal adhesion formation in an in vivo model.Methods: Anesthetized New Zealand white rabbits underwent cecal sidewall abrasion surgery in which the cecal ...
Eun Seok Gil, Elton Aleksi, Lisa Spirio
doaj   +4 more sources

Noninvasive endoscopic hemostasis technique for post‐papillectomy bleeding using a novel self‐assembling peptide (with video) [PDF]

JGH Open, 2023
Although a novel hemostatic agent has been used for endoscopic mucosal resection in submucosal dissection, there are few case reports of its use in pancreato‐biliary endoscopic procedures.
Akira Miyano, Takeshi Ogura, Hiroki Nishikawa   +2 more
doaj   +3 more sources

Purastat as an Adjunct Treatment Option in Acute Esophageal Varices Bleeding: A Case Report. [PDF]

Cureus, 2023
Esophageal varices are dilated submucosal esophageal veins that connect the portal and systemic circulations. Bleeding esophageal varices is a well-recognized complication of liver cirrhosis.It is known that in active variceal bleeding, treatment needs to be started promptly.
Hassan IH, Elphick D, Al-Rifaie A.
europepmc   +5 more sources

Impact of Using Self-Assembling Peptide (PuraStat) on Anastomotic Ulcers-A Multicenter Case Series. [PDF]

ACG Case Rep J
ABSTRACT Treatment of anastomotic ulcers, also known as marginal ulcers, is challenging, especially when established techniques have failed. PuraStat is a biocompatible synthetic peptide gel that is indicated for hemostasis of bleeding in the gastrointestinal tract and vascular anastomoses.
Oza VM, Mittal N, Winchester C, Fazel Y, Manvar A, Goodman A, Girotra M, Khara HS, Kothari S, Kothari TH.   +9 more
europepmc   +4 more sources

Cystoscopic application of PuraStat^® in the treatment of radiation-induced haemorrhagic cystitis. [PDF]

Ann R Coll Surg Engl
The use of radiotherapy has increased in recent years, especially for pelvic neoplasms, and this can result in long-term complications such as recurrent haemorrhagic radiation cystitis (RHC). A 73-year-old male patient presented to a hospital emergency department multiple times with visible haematuria and clots leading to urinary clot retention; he ...
Darwazeh H, Hemsworth L, Smith L, Ilie PC.   +3 more
europepmc   +4 more sources

Efficacy of hemostatic gel for perioperative bleeding and prevention of delayed bleeding of cold snare polypectomy under anticoagulant [PDF]

JGH Open
Background and Aim A hemostatic gel, PuraStat (3‐D Matrix, Tokyo, Japan), is used for various gastrointestinal hemostasis. In this study, we analyzed the efficacy of PuraStat for perioperative bleeding (POB) and prevention of delayed bleeding (DB) to ...
Naohisa Yoshida, Osamu Dohi, Yoshikazu Inagaki, Yuri Tomita, Hikaru Hashimoto, Reo Kobayashi, Ken Inoue, Ryohei Hirose, Yasutaka Morimoto, Yutaka Inada, Takaaki Murakami, Yoshito Itoh   +11 more
doaj   +3 more sources

Off-label PuraStat use for the treatment of acute intrahepatic biliary duct bleeding [PDF]

Endoscopy International Open, 2021
Paola Soriani, Paolo Biancheri, Simona Deiana, Laura Ottaviani, Mauro Manno   +4 more
doaj   +4 more sources

Hemostasis: Role of PuraStat^® in the prevention and management of gastrointestinal bleeding. [PDF]

World J Gastrointest Endosc
The management of gastrointestinal (GI) bleeding patients during endoscopy remains a challenge. Hemorrhage is still one of the significant causes of morbidity and even death. Several therapeutic options have been used over the years depending on the extent, site and cause of bleeding.
Azer SA.
europepmc   +3 more sources

PuraStat in gastrointestinal bleeding: results of a prospective multicentre observational pilot study [PDF]

Surgical Endoscopy, 2021
Abstract Background A recently developed haemostatic peptide gel for endoscopic application has been introduced to improve the management of gastrointestinal bleeding. The aim of this pilot study was to evaluate the feasibility, safety, efficacy and indication profiles of PuraStat in a clinical setting.
Federica Branchi, Rolf D. Klingenberg-Noftz, Kristina Friedrich, Nataly Bürgel, S Daum, Juliane Buchkremer, Elena Sonnenberg, Michael Schümann, Christoph Treese, Hanno Tröger, Donata Lissner, Hans–Jörg Epple, Britta Siegmund, Andrea Stroux, Andreas Adler, Winfried Veltzke-Schlieker, Daniel Autenrieth, Silke Leonhardt, Andréas Fischer, Christian Jürgensen, Ulrich‐Frank Pape, Bertram Wiedenmann, O Möschler, Maximilian Schreiner, Mathias Z. Strowski, Volkmar Hempel, Yvonne Huber, Helmut Neumann, Christian Bojarski   +28 more
openalex   +5 more sources

P75 Comparison between 4% formalin instillation and purastat application for radiation proctopathy [PDF]

Posters, 2021
Introduction Formalin therapy is an established method for the treatment of radiation proctopathy (RP). Emerging data suggests a potential role for Purastat application in the treatment of RP; however, no comparison to conventional treatment has been made to date.
Matthew Stammers, Philip Boger, Praful Patel, Imdadur Rahman   +3 more
openalex   +3 more sources