Results 21 to 30 of about 358 (116)

Endoscopic Application of Purastat® in the Treatment of Solitary Rectal Ulcer Syndrome

Journal of Gastrointestinal and Liver Diseases, 2021
A 49-years-old woman with a recent history of tenesmus, constipation, abdominal and rectal pain referred to our Unit. There was no previous history of rectal bleeding or a family history of gastrointestinal diseases. Laboratory tests showed haemoglobin 10.9 g/dl, MCV 72fl, ferritin 18 U/l. Physical examination was normal.
Mario Gagliardi, M. Sica, Giovanni Oliviero, Attilio Maurano, Claudio Zulli   +4 more
  +7 more sources

Clip Closure and PuraStat for Prevention of Clinically Significant Delayed Bleeding after Colorectal Endoscopic Submucosal Dissection: A Prospective, Observational Study [PDF]

Gastroenterology Insights
Background and aims. Clinically significant delayed bleeding (CSDB) may complicate endoscopic colorectal submucosal dissection (ESD). We aimed to assess the efficacy of preventive measures for CSDB. Methods.
Mihai Ciocîrlan, Dana Bilous, Andrei Gîla, Daniel-Corneliu Leucuta, Daniela Mihailă, Adrian Tulin, Anca Gheorghiu, Elena Tianu, Cătălina Vlăduț   +8 more
doaj   +3 more sources

Emergency Endoscopic Hemostasis for Gastrointestinal Bleeding Using a Self-Assembling Peptide: A Case Series [PDF]

Medicina, 2023
Background and Objectives: A novel synthetic self-assembling peptide, PuraStat, has been introduced as a hemostatic agent. This case series aimed to evaluate the clinical efficacy of PuraStat for gastrointestinal bleeding during emergency endoscopy ...
Takashi Murakami, Eiji Kamba, Keiichi Haga, Yoichi Akazawa, Hiroya Ueyama, Tomoyoshi Shibuya, Mariko Hojo, Akihito Nagahara   +7 more
doaj   +2 more sources

Polyglycolic Acid Sheet Application to Refractory Delayed Bleeding After Rectal Endoscopic Submucosal Dissection: A Case Report [PDF]

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT A man in his 50s underwent endoscopic submucosal dissection (ESD) for a rectal tumor measuring 28 mm. He was not taking any antithrombotic medication. On the third, 11th, 18th, and 24th days after the procedure, bleeding was observed from different areas of the ulcer bed margin and was managed with hemostatic forceps.
Yoshiko Nakano, Katsutoshi Kuriyama, Yasuhiro Watanabe, Shin'ichi Miyamoto   +3 more
wiley   +2 more sources

A Multi-Centre, Single-Arm Clinical Study to Confirm Safety and Performance of PuraStat®, for the Management of Bleeding in Elective Carotid Artery Surgery

Clinical and Applied Thrombosis/Hemostasis, 2022
Anastomotic bleeding in vascular surgery can be difficult to control. Patients, in particular those undergoing carotid surgery, have often been started on treatment with dual antiplatelet agents and receive systemic heparinization intraoperatively.
Katherine M. Stenson MA, MBBS, MD, FRCS, Ian M. Loftus MD, FRCS, Ian Chetter MD, FRCS, Inge Fourneau PhD, MD, Stephen Cavanagh FRCS, Colin Bicknell MD, FRCS, Paros Loftus MBBS   +6 more
doaj   +2 more sources

A clear approach: Hemostatic gel as a novel adjunct for pediatric upper gastrointestinal bleeding [PDF]

JPGN Reports, Volume 6, Issue 2, Page 157-161, May 2025.
Abstract Pediatric upper gastrointestinal bleeding (UGIB) is a significant clinical concern, with a mortality rate of approximately 2%. Endoscopic management of UGIB in children includes various techniques such as injections, mechanical devices, thermal therapies, and topical agents.
Natalia Plott, Audra Rougraff, Paroma Bose, Kyla M. Tolliver, Shamaila Waseem, Brett J. Hoskins   +5 more
wiley   +2 more sources

PWE-048 Endoscopically-delivered purastat for the treatment of severe haemorrhagic radiation proctopathy: a case series [PDF]

Posters, 2019
Introduction 30,000 people are treated with pelvic radiotherapy annually in the UK. Rectal bleeding is common following pelvic radiotherapy,one of the main causes being radiation proctopathy (RP). Radiation causes ischaemia and fibrosis,leading to neovascularisation with small friable vessels which are the source of bleeding.
Katherine White, Caroline Henson
openalex   +3 more sources

Use of Purastat, a novel haemostatic matrix based on self-assembling peptides in the prevention of nasopharyngeal adhesion formation

International Journal of Surgery Case Reports, 2020
Purastat is a novel haemostatic agent that has recently been used effectively in nasal procedures, specifically in functional endoscopic endonasal surgery in the prevention of post-operative epistaxis while minimising adhesion formation. This study presents a case of successful application of Purastat following division of a nasopharyngeal/palatal ...
Eugene Wong, Joyce Ho, M. J. Smith, Niranjan Sritharan, Faruque Riffat, Mark C. Smith   +5 more
openalex   +3 more sources

Post-polypectomy colorectal bleeding: current strategies and the way forward [PDF]

Clinical Endoscopy
Post-endoscopic mucosal resection (EMR) bleeding, or clinically significant post-EMR bleeding, is influenced by factors such as polyp size, right-sided colonic lesions, laterally spreading tumors, anticoagulant use, and comorbidities like cardiovascular ...
Nilanga Nishad, Mo Hameed Thoufeeq
doaj   +2 more sources

Endoscopically delivered Purastat for the treatment of severe haemorrhagic radiation proctopathy: a service evaluation of a new endoscopic treatment for a challenging condition

Frontline Gastroenterology, 2021
BackgroundA total of 30 000 people are treated with pelvic radiotherapy annually in the UK. Rectal bleeding is common following pelvic radiotherapy and one of the main causes is radiation proctopathy (RP). Six per cent develop severe bleeding from RP, leading to anaemia requiring iron +/− blood transfusion.
Katherine White, Caroline Henson
openalex   +5 more sources