Results 121 to 130 of about 46,457 (296)
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Exchange Rate Misalignment in Pakistan: Evidence from Purchasing Power Parity Theory [PDF]
This paper examines the validity of the purchasing power parity to evaluate whether the Pakrupee vis-à-vis the US-dollar has been overvalued since the introduction of managed floating exchange rate.
Abdul Qayyum +2 more
core
The role of integral emotions in female consumers’ clothing purchasing decision [PDF]
The Retail and Marketing Review, 2018 The clothing purchasing decision can be an emotional process. Typically, emotions are induced when consumers consider the various evaluative criteria as relevant for their concerns or goals they want to achieve through clothing (Lazarus 2001). Lerner and
Dr J Kasambala +2 more
doaj
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Implementing e-purchasing framework in construction organizations / Rafikullah Bin Deraman [PDF]
, 2014 Studies have shown that the use of electronic purchasing or e-Purchasing saves organizations millions of dollars yearly in transaction related costs.
Deraman, Rafikullah
core
Purchasing decisions at private hospitals in the framework of resource dependency theory
Independent Journal of Management & Production, 2017 The environment influencing hospitals in the health industry is quite complicated, and despite the high volume of inputs, the functions that occur at purchasing level are very intricate. The reason that the feedback mechanism of health services is not organized completely, and thus another reason that the health system is quite complicated, is ...
openaire +5 more sources
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Икономика и управление на селското стопанствоNutritional claims refer to statements or labels on food and beverage products that highlight their nutritional content, health benefits, or ingredient-related attributes.
S. S. K. De Silva +3 more
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source